{"id":"W2141219606","doi":"10.1093/toxsci/kfm303","title":"Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment","year":2007,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Health Canada","funders":"National Institute of Environmental Health Sciences; Natural Sciences and Engineering Research Council of Canada","keywords":"Environmental chemistry; Pyrene; Fish <Actinopterygii>; Toxicity; Biotransformation; Chemistry; Carcinogen; Benzo(a)pyrene; Developmental toxicity; Biology; Organic chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009325912,0.001066063,0.0009096239,0.001188981,0.0004060974,0.00132225,0.000798677,0.001626019,0.002378107],"category_scores_gemma":[0.0009204833,0.000296208,0.0006726758,0.0007582732,0.0007380539,0.001218745,0.0008765666,0.0006857099,0.0003507014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007741772,"about_ca_system_score_gemma":0.0007679185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001435314,"about_ca_topic_score_gemma":0.001960382,"domain_scores_codex":[0.9995808,0.0001395338,0.00003381335,0.00007304278,0.0001413919,0.00003134408],"domain_scores_gemma":[0.9992286,0.0003395193,0.000225227,0.00003721515,0.00011255,0.00005691043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001103596,0.0006071329,0.07886843,0.007740675,0.0007662625,0.003372067,0.0005824642,0.03084032,0.1609861,0.03517668,0.003304816,0.6766515],"study_design_scores_gemma":[0.0001794969,0.006688938,0.3371869,0.002144422,0.002369139,0.01851097,0.002504685,0.04512449,0.2083434,0.2334344,0.1430615,0.0004517228],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2746671,0.569483,0.1213878,0.009484514,0.0002638521,0.0002064446,0.001231006,0.0003977504,0.02287848],"genre_scores_gemma":[0.6624446,0.3021706,0.02841263,0.0006892653,0.0002235362,0.0001251436,0.0004353551,0.0000266767,0.005472218],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002378107,"threshold_uncertainty_score":0.007955551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01762781298446267,"score_gpt":0.2932226040966107,"score_spread":0.275594791112148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}