{"id":"W2141284512","doi":"10.1158/1078-0432.ccr-10-1551","title":"Array-Based Comparative Genomic Hybridization Identifies <i>CDK4</i> and <i>FOXM1</i> Alterations as Independent Predictors of Survival in Malignant Peripheral Nerve Sheath Tumor","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University Health Network","funders":"","keywords":"Comparative genomic hybridization; Biology; FOXM1; Candidate gene; Malignant peripheral nerve sheath tumor; Tissue microarray; Cancer research; Fluorescence in situ hybridization; Microarray; Microarray analysis techniques; Copy-number variation; Cancer; Gene expression profiling; Gene; In situ hybridization; Immunohistochemistry; Pathology; Gene expression; Genetics; Cell cycle; Genome; Medicine; Chromosome; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002824754,0.0002009428,0.0001666722,0.0004705545,0.00009560107,0.0001463854,0.0001269019,0.0001441074,0.0005678304],"category_scores_gemma":[0.0006423989,0.00008486233,0.0001180229,0.0002295437,0.0002250648,0.00009533534,0.00009303923,0.0001738355,0.00008275497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000180023,"about_ca_system_score_gemma":0.0000995195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000671109,"about_ca_topic_score_gemma":0.0007101819,"domain_scores_codex":[0.9998887,0.00002987261,0.000007344542,0.00003171068,0.00002403977,0.00001822409],"domain_scores_gemma":[0.9997388,0.0001231539,0.0000752238,0.00001624469,0.00001841225,0.00002823029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001583014,0.00007851086,0.8553787,0.00004460881,0.000099283,0.0002619706,0.00005938928,0.0009630207,0.1293974,0.0000506254,0.0001628911,0.0119207],"study_design_scores_gemma":[0.00004014936,0.0003895398,0.9699627,0.000004635077,0.0000826234,0.001026021,0.00004741845,0.003573827,0.02447155,0.00009538143,0.0002995781,0.000006596713],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993392,0.0001261451,0.0003658391,0.0000134684,0.000001056331,0.000002390393,0.00005635065,0.000008060139,0.00008744148],"genre_scores_gemma":[0.9992691,0.0000418466,0.0004907076,0.000008263284,0.000003940017,0.000005618382,0.0001302111,0.000001221837,0.00004920016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000671109,"threshold_uncertainty_score":0.00189954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2229361302795161,"score_gpt":0.4414306515887627,"score_spread":0.2184945213092466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}