{"id":"W2141287168","doi":"10.1002/adsc.200505248","title":"Synthesis of Aryl‐Substituted 1,4‐Benzoquinone <i>via</i> Water‐Promoted and In(OTf)<sub>3</sub>‐Catalyzed <i>in situ</i> Conjugate Addition‐Dehydrogenation of Aromatic Compounds to 1,4‐Benzoquinone in Water","year":2006,"lang":"en","type":"article","venue":"Advanced Synthesis & Catalysis","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Chemistry; Dehydrogenation; Regioselectivity; Catalysis; Conjugate; Nucleophile; Aryl; Medicinal chemistry; Quinone; In situ; 1,4-Benzoquinone; Benzoquinone; Nucleophilic addition; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001076188,0.000531997,0.001351735,0.001159663,0.0001326014,0.00002239894,0.0004002635,0.0003380722,0.00008441324],"category_scores_gemma":[0.0001771348,0.0004621802,0.0002098851,0.0009819202,0.0003852601,0.0004821742,0.0001763694,0.000382692,0.00005014468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002074957,"about_ca_system_score_gemma":0.00003944142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004124347,"about_ca_topic_score_gemma":0.002610398,"domain_scores_codex":[0.9961151,0.0003424429,0.001554208,0.0008015551,0.0003660822,0.0008205617],"domain_scores_gemma":[0.9979205,0.0009473449,0.0003543443,0.000471731,0.0001300563,0.0001760389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007700523,0.001432858,0.006824032,0.000235802,0.0002007199,0.00009653054,0.0004174779,0.002767614,0.9819689,0.00001849152,0.00002574609,0.005241799],"study_design_scores_gemma":[0.001600041,0.00004888206,0.01394225,0.000328104,0.0003222615,0.00001979746,0.0001165473,0.0008886941,0.9815515,0.0005554791,0.00009569819,0.0005307369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976659,0.0003015742,0.0001856543,0.000344386,0.0001451908,0.0007828897,0.0002185171,0.00004957741,0.000306244],"genre_scores_gemma":[0.9983658,0.0002327946,0.0003640649,0.0001071427,0.00003597424,0.0003429809,0.0004857322,0.00005499369,0.00001049698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007118213,"threshold_uncertainty_score":0.999783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02112138670805138,"score_gpt":0.2975020099596398,"score_spread":0.2763806232515884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}