{"id":"W2141287168","doi":"10.1002/adsc.200505248","title":"Synthesis of Aryl‐Substituted 1,4‐Benzoquinone <i>via</i> Water‐Promoted and In(OTf)<sub>3</sub>‐Catalyzed <i>in situ</i> Conjugate Addition‐Dehydrogenation of Aromatic Compounds to 1,4‐Benzoquinone in Water","year":2006,"lang":"en","type":"article","venue":"Advanced Synthesis & Catalysis","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Chemistry; Dehydrogenation; Regioselectivity; Catalysis; Conjugate; Nucleophile; Aryl; Medicinal chemistry; Quinone; In situ; 1,4-Benzoquinone; Benzoquinone; Nucleophilic addition; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008607696,0.0003475003,0.0001742286,0.00007886427,0.0001404843,0.000142062,0.0002307682,0.0001582126,0.001520635],"category_scores_gemma":[0.0001118162,0.000166672,0.0001532657,0.00009572103,0.0001603531,0.00020757,0.0001382528,0.0002157685,0.0003894393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012521,"about_ca_system_score_gemma":0.0002952058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005489233,"about_ca_topic_score_gemma":0.001006689,"domain_scores_codex":[0.9999484,0.000006769185,0.000003724791,0.00001386787,0.00001094842,0.00001637335],"domain_scores_gemma":[0.999936,0.000008847098,0.00002361923,0.000007883599,0.000009873869,0.00001378021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004158638,0.00001139565,0.00005902612,0.00007403725,0.00000298028,0.00005265079,0.00003072025,0.0001363118,0.9973041,0.0002022759,0.00004977689,0.002035095],"study_design_scores_gemma":[0.00001030394,0.0001453131,0.0002793247,0.000001527684,0.000005145521,0.00005559273,0.000006389923,0.0001564504,0.9973205,0.00002888555,0.001986557,0.000004039729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765708,0.001202373,0.01584585,0.00009020525,0.00006518436,0.00009982145,0.0004197808,0.0001646383,0.005541186],"genre_scores_gemma":[0.9910574,0.0005783005,0.005642901,0.00001570858,0.000004528107,0.0000283065,0.0001119867,0.00001833139,0.002542612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001520635,"threshold_uncertainty_score":0.005087018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02112138670805138,"score_gpt":0.2975020099596398,"score_spread":0.2763806232515884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}