{"id":"W2141325836","doi":"10.1158/1078-0432.ccr-06-0252","title":"Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes","year":2006,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University Health Network; University of Toronto; BC Cancer Agency","funders":"BC Cancer Agency; Immunodeficiency Canada","keywords":"Pathology; Biology; Adenocarcinoma; Cancer; Carcinoma; Fluorescence in situ hybridization; Transplantation; Lung cancer; Carcinosarcoma; Cancer research; Adenosquamous carcinoma; Tumor progression; Medicine; Internal medicine; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001133617,0.0001771125,0.0004816214,0.0001256477,0.000154949,0.00003417305,0.0002995664,0.0001301447,0.00002252677],"category_scores_gemma":[0.0000441884,0.0001546398,0.0001169711,0.0002833451,0.0004241685,0.00001961529,0.0002060699,0.0003038147,1.526631e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001393137,"about_ca_system_score_gemma":0.0007150976,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02363311,"about_ca_topic_score_gemma":0.006360061,"domain_scores_codex":[0.9974635,0.0002476008,0.0006601625,0.0005943035,0.0004697768,0.0005646968],"domain_scores_gemma":[0.99893,0.0001128945,0.0001779999,0.0002866861,0.0003784332,0.0001139552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01101047,0.00337696,0.1094161,0.001416973,0.0006251032,0.00006124732,0.0004370704,0.002010573,0.8632277,0.00009291399,0.001432134,0.006892702],"study_design_scores_gemma":[0.06529877,0.01554567,0.241346,0.003333972,0.0004627896,0.00002909052,0.001042438,0.01405186,0.6520678,0.004370113,0.0009052096,0.001546353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847143,0.012867,0.0000625245,0.0000989507,0.00008233007,0.001237062,0.0008129367,0.000006425692,0.0001184695],"genre_scores_gemma":[0.9970537,0.001445146,0.000269652,0.00001799365,0.0001316735,0.0004849158,0.00048351,0.00002702461,0.00008638454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.21116,"threshold_uncertainty_score":0.9828686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06316110491169903,"score_gpt":0.4074269763729917,"score_spread":0.3442658714612927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}