{"id":"W2141325836","doi":"10.1158/1078-0432.ccr-06-0252","title":"Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes","year":2006,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University Health Network; University of Toronto; BC Cancer Agency","funders":"BC Cancer Agency; Immunodeficiency Canada","keywords":"Pathology; Biology; Adenocarcinoma; Cancer; Carcinoma; Fluorescence in situ hybridization; Transplantation; Lung cancer; Carcinosarcoma; Cancer research; Adenosquamous carcinoma; Tumor progression; Medicine; Internal medicine; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009582278,0.0009996607,0.0004442643,0.0008541921,0.0002902336,0.000516244,0.000649291,0.0005195185,0.002464249],"category_scores_gemma":[0.0002432036,0.000380362,0.0006941371,0.0003393524,0.0004846555,0.0005890712,0.000397853,0.001381034,0.0007153295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003733197,"about_ca_system_score_gemma":0.0004356335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006440958,"about_ca_topic_score_gemma":0.001347536,"domain_scores_codex":[0.9995139,0.00007736868,0.00006666304,0.0001219346,0.0001416998,0.00007855334],"domain_scores_gemma":[0.9993987,0.0001182758,0.0001824796,0.0001361836,0.00003747852,0.0001268195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003020843,0.0002780259,0.000579329,0.00005616902,0.00001620218,0.0001413913,0.00003292114,0.0001286299,0.9969059,0.0003503233,0.00007324285,0.001135914],"study_design_scores_gemma":[0.0002127662,0.003139603,0.008084627,0.00002960195,0.00009246195,0.001918671,0.00007205478,0.002578939,0.9777868,0.0001324099,0.005934485,0.00001760982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9698527,0.001676569,0.02277959,0.0001501145,0.00008325594,0.000661078,0.002097675,0.0003104508,0.002388603],"genre_scores_gemma":[0.9549569,0.001960506,0.02981881,0.0001168532,0.00003823313,0.0009704133,0.006191874,0.0001169357,0.005829378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002464249,"threshold_uncertainty_score":0.00824368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06316110491169903,"score_gpt":0.4074269763729917,"score_spread":0.3442658714612927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}