{"id":"W2141354880","doi":"10.1136/gut.48.5.630","title":"Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat","year":2001,"lang":"en","type":"article","venue":"Gut","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":307,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Mast cell; Barrier function; Epithelium; Inflammation; Immune system; Hyperplasia; Chronic stress; Pathology; Immunology; Medicine; Biology; Endocrinology; Chemistry; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001839678,0.00008827679,0.0001571205,0.00008950364,0.00004150295,0.000004759264,0.0001540842,0.0001553971,0.001163185],"category_scores_gemma":[0.00000938436,0.00006638339,0.00003549543,0.000150635,0.00007042155,0.00003343009,0.00003014842,0.0002395967,0.0001884124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006731456,"about_ca_system_score_gemma":0.00007359182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008723823,"about_ca_topic_score_gemma":0.006048587,"domain_scores_codex":[0.9992557,0.0001446038,0.0002092825,0.0001439756,0.00002586897,0.0002205381],"domain_scores_gemma":[0.9996744,0.00004993461,0.00006471683,0.0001874357,0.00001630027,0.0000072272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001203436,0.0001061232,0.002589773,0.00001072571,0.000009116384,0.000005760249,0.0007937191,0.00004840316,0.9928994,0.0002037336,0.0001964671,0.003016447],"study_design_scores_gemma":[0.005103766,0.0008483301,0.06967906,0.00008022548,0.0000306988,0.00003231364,0.002072747,0.00007315263,0.6937647,0.0001987804,0.2278401,0.000276105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951811,0.001117519,0.000003189249,0.00007766141,0.0003373488,0.000184882,0.00002345357,0.000006947403,0.003067841],"genre_scores_gemma":[0.9977599,0.0001253417,0.000002336043,0.00004417095,0.00003955925,0.0000175833,0.00003475094,0.000006336458,0.001970035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2991347,"threshold_uncertainty_score":0.9997499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007930678858964436,"score_gpt":0.2092333801636598,"score_spread":0.2013027013046954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}