{"id":"W2141405139","doi":"10.4049/jimmunol.1201787","title":"Autoantigen Recognition Is Required for Recruitment of IGRP206–214-Autoreactive CD8+ T Cells but Is Dispensable for Tolerance","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Biology; CD8; Cell biology; Immunology; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000932132,0.000256623,0.0002879792,0.0001100606,0.0001203161,0.0003740459,0.0002334355,0.0003106117,0.001519217],"category_scores_gemma":[0.0001636799,0.0001794766,0.0001810022,0.0001005915,0.0002806896,0.0001954958,0.0002970525,0.0006553783,0.0007580416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001987841,"about_ca_system_score_gemma":0.0002163249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001893024,"about_ca_topic_score_gemma":0.0002478278,"domain_scores_codex":[0.9997891,0.00002814335,0.00002413815,0.00006104411,0.00004571944,0.00005184052],"domain_scores_gemma":[0.9996394,0.0000370967,0.0001434038,0.00004035342,0.00001882129,0.0001210147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007321331,0.000008720449,0.0002152817,0.00001290408,0.000001330761,0.00004947374,0.000005356459,0.00001036944,0.9992637,0.0000179978,0.00000789386,0.00033374],"study_design_scores_gemma":[0.00002032426,0.0003994783,0.03037248,0.00001278766,0.00001633399,0.001030282,0.00005873129,0.0005885268,0.9656062,0.00007322107,0.001813772,0.00000786193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976255,0.0005893744,0.000790388,0.00004130208,0.00001749017,0.000007314876,0.0001536239,0.00006436621,0.0007105572],"genre_scores_gemma":[0.9975699,0.0002110355,0.0007021843,0.00004105462,0.000008490047,0.00001704779,0.0002740923,0.00002661671,0.001149537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519217,"threshold_uncertainty_score":0.00508225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06011617082565743,"score_gpt":0.2823986366240052,"score_spread":0.2222824657983477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}