{"id":"W2141447309","doi":"10.1517/14728222.4.4.541","title":"The insulin receptor kinase: modulation and therapeutic implications","year":2000,"lang":"en","type":"article","venue":"Emerging Therapeutic Targets","topic":"Vanadium and Halogenation Chemistry","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"Autophosphorylation; Insulin receptor; Cell biology; Insulin; Biology; Phosphorylation; Protein kinase A; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004115604,0.0004219888,0.0004655444,0.0005175195,0.0001169844,0.0007351131,0.0003950096,0.0009318735,0.00291189],"category_scores_gemma":[0.0003154068,0.0001093042,0.0003477431,0.0004323996,0.0003778288,0.0006245697,0.0002874665,0.001773623,0.001259501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004489535,"about_ca_system_score_gemma":0.0002148292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001353261,"about_ca_topic_score_gemma":0.0002131678,"domain_scores_codex":[0.9998686,0.00003116919,0.00001038276,0.00002933662,0.00003865549,0.00002181466],"domain_scores_gemma":[0.9999198,0.00002186748,0.00001850523,0.000007106288,0.00001768407,0.00001517031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001618106,0.0008779713,0.0008687949,0.003290463,0.00008715047,0.001543852,0.00009098613,0.000696721,0.08092535,0.01699576,0.0195103,0.8734945],"study_design_scores_gemma":[0.0005090649,0.003446386,0.005938285,0.001380853,0.0002051078,0.01044559,0.0001538095,0.001067154,0.03541194,0.01446504,0.9269196,0.00005716824],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01194007,0.9647651,0.001826697,0.007093996,0.001122107,0.00002421214,0.0000927623,0.00005547845,0.01307962],"genre_scores_gemma":[0.1550092,0.8243208,0.003248249,0.005346478,0.00270854,0.00007549229,0.0002266933,0.00003121978,0.009033404],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00291189,"threshold_uncertainty_score":0.009741247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526397074828812,"score_gpt":0.2560361876563313,"score_spread":0.2407722169080432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}