{"id":"W2141478099","doi":"10.1128/jvi.76.21.10637-10653.2002","title":"PKR-Dependent Mechanisms of Gene Expression from a Subgenomic Hepatitis C Virus Clone","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Subgenomic mRNA; Internal ribosome entry site; Biology; Protein kinase R; Replicon; Virology; Molecular biology; Protein biosynthesis; Viral replication; Interferon; Phosphorylation; Virus; Translation (biology); RNA; Protein kinase A; Messenger RNA; Gene; Cell biology; Cyclin-dependent kinase 2; Plasmid; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002055407,0.000415722,0.0002811243,0.0003190399,0.0001870766,0.000373082,0.0002179304,0.0001945132,0.00130315],"category_scores_gemma":[0.0002006962,0.0002044465,0.0004167582,0.0001764935,0.0002773754,0.0002684017,0.0002981611,0.0006350638,0.0007088441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005515169,"about_ca_system_score_gemma":0.0003146047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004948006,"about_ca_topic_score_gemma":0.0005845117,"domain_scores_codex":[0.9997485,0.00003413274,0.00002099066,0.00006984868,0.00008577502,0.00004070447],"domain_scores_gemma":[0.999817,0.000055784,0.00003297014,0.00004319212,0.00002845219,0.00002257592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004672603,0.00001065353,0.00006431899,0.00003252442,0.000002392424,0.00002111795,0.00001256629,0.00002730607,0.9984806,0.0001724331,0.00002314943,0.00110622],"study_design_scores_gemma":[0.000008504572,0.0002331233,0.002540139,0.000005357406,0.0000109395,0.0002296509,0.00001092121,0.0005942195,0.9937323,0.00006867677,0.00256164,0.000004569463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648492,0.006081612,0.02088152,0.0001901583,0.000116867,0.0001891776,0.001458958,0.0002757784,0.005956764],"genre_scores_gemma":[0.9687074,0.003438862,0.01417543,0.0001079486,0.00005333632,0.0001773923,0.004164836,0.00007540213,0.009099429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00130315,"threshold_uncertainty_score":0.004359424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00992134721437286,"score_gpt":0.2226248057744094,"score_spread":0.2127034585600366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}