{"id":"W2141478099","doi":"10.1128/jvi.76.21.10637-10653.2002","title":"PKR-Dependent Mechanisms of Gene Expression from a Subgenomic Hepatitis C Virus Clone","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Subgenomic mRNA; Internal ribosome entry site; Biology; Protein kinase R; Replicon; Virology; Molecular biology; Protein biosynthesis; Viral replication; Interferon; Phosphorylation; Virus; Translation (biology); RNA; Protein kinase A; Messenger RNA; Gene; Cell biology; Cyclin-dependent kinase 2; Plasmid; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009970261,0.00009214114,0.0002027671,0.00006155699,0.00002642727,0.000005553184,0.0001546994,0.0001445763,0.0005698373],"category_scores_gemma":[0.00004196475,0.00008028209,0.000132048,0.00002621544,0.00004308245,0.000004863866,0.0000426318,0.0000716872,0.00001353947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001174345,"about_ca_system_score_gemma":0.0000239197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004518625,"about_ca_topic_score_gemma":0.00002526435,"domain_scores_codex":[0.999153,0.00009266534,0.0003722146,0.0001284302,0.0001353769,0.0001183122],"domain_scores_gemma":[0.9992331,0.00001206033,0.0003778775,0.0001861188,0.00008080411,0.0001101016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002553315,0.0001355827,0.003438728,0.00000262408,0.00004874186,0.00002913379,0.00002960351,0.0001838999,0.9942859,0.0000317738,0.0009993133,0.0005594015],"study_design_scores_gemma":[0.001217089,0.0005677598,0.02048964,0.000006523928,0.00003987783,0.00007378377,0.00001084198,0.0001621652,0.9754329,0.0008820008,0.00102998,0.00008747441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831008,0.001885369,0.01442687,0.0001612696,0.0002303077,0.00004539407,0.00003775823,0.000002135324,0.0001101031],"genre_scores_gemma":[0.9956042,0.0009629052,0.002717132,0.0003193995,0.0002195253,0.000001399684,0.00001443618,0.0000118699,0.0001491565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01885301,"threshold_uncertainty_score":0.6239318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00992134721437286,"score_gpt":0.2226248057744094,"score_spread":0.2127034585600366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}