{"id":"W2141532801","doi":"10.1210/en.2008-0088","title":"Insulin and Dexamethasone Dynamically Regulate Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1","year":2008,"lang":"en","type":"article","venue":"Endocrinology","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Children’s Health Research Institute; Lawson Health Research Institute","funders":"","keywords":"Endocrinology; Internal medicine; Adipocyte; Dexamethasone; 11β-hydroxysteroid dehydrogenase type 1; Dehydrogenase; Hydroxysteroid dehydrogenase; Insulin; Medicine; Biology; Enzyme; Adipose tissue; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005205479,0.0001562559,0.0003661348,0.0001491203,0.0001041579,0.000004397918,0.00005530761,0.0001117225,0.0001801551],"category_scores_gemma":[0.0001616409,0.000133284,0.00005313248,0.0001580848,0.0002369466,0.00004799432,0.00006582032,0.0002089242,0.0002175148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004597359,"about_ca_system_score_gemma":0.00007916323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003363797,"about_ca_topic_score_gemma":0.00001488195,"domain_scores_codex":[0.9988777,0.00006016448,0.0002480448,0.0003105925,0.0001605444,0.0003429602],"domain_scores_gemma":[0.9992832,0.0000676218,0.00005462515,0.000279056,0.0001082587,0.000207257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003585235,0.0006500464,0.04832707,0.0001114046,0.0005664577,0.01268858,0.0008326583,0.00005800424,0.8238907,0.00665889,0.00298307,0.09964783],"study_design_scores_gemma":[0.008935302,0.001926002,0.732084,0.00007694485,0.0002394856,0.04887415,0.00005200906,0.01172712,0.03616291,0.0006033304,0.158759,0.0005597148],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924179,0.003339941,0.0000851752,0.001730635,0.000119374,0.0001915718,0.000002052453,0.0001095762,0.002003802],"genre_scores_gemma":[0.9935567,0.00118662,0.001740596,0.0009568719,0.00008809487,0.000005812658,0.00002213733,0.00002523026,0.002417891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7877278,"threshold_uncertainty_score":0.5435163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03073441523200074,"score_gpt":0.2647594380943865,"score_spread":0.2340250228623857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}