{"id":"W2141549067","doi":"10.2174/138920210793175895","title":"MicroRNA: Biogenesis, Function and Role in Cancer","year":2010,"lang":"en","type":"article","venue":"Current Genomics","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1835,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Gene silencing; microRNA; Argonaute; RNA-induced silencing complex; Biology; Cell biology; Dicer; RNA; Small RNA; RNA silencing; RNA interference; Computational biology; Genetics; Gene; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003656278,0.0003683575,0.0004880392,0.0004187318,0.0003748685,0.0008323808,0.0003161348,0.0007292667,0.002121908],"category_scores_gemma":[0.0003600202,0.0001127682,0.0002187736,0.0007115568,0.0004895899,0.0005365356,0.0004946938,0.0006454714,0.001635972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006066655,"about_ca_system_score_gemma":0.0006482852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004937292,"about_ca_topic_score_gemma":0.0003565955,"domain_scores_codex":[0.9998001,0.00003955528,0.0000169,0.00005615916,0.00005929689,0.00002784168],"domain_scores_gemma":[0.9998839,0.0000174001,0.00002904521,0.000007260894,0.00003160462,0.0000307971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007882818,0.0001344355,0.004164105,0.00437427,0.0001321443,0.001764459,0.0003216311,0.0009946263,0.1791746,0.02811977,0.05863043,0.7214013],"study_design_scores_gemma":[0.00004987555,0.0005644609,0.01519721,0.0005433494,0.0001514331,0.007522237,0.0001660932,0.0008854821,0.03455643,0.01123414,0.9290758,0.00005348458],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01486025,0.9624759,0.003786679,0.003170328,0.001099249,0.00004857637,0.0004946382,0.0002304506,0.01383391],"genre_scores_gemma":[0.2889534,0.6762311,0.008568529,0.002190659,0.001805776,0.0001790729,0.0010073,0.0001100909,0.02095412],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002121908,"threshold_uncertainty_score":0.007098436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00983212898421194,"score_gpt":0.2554013615007473,"score_spread":0.2455692325165354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}