{"id":"W2141558659","doi":"10.1371/journal.pgen.1002756","title":"G Protein Activation without a GEF in the Plant Kingdom","year":2012,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Basic Energy Sciences; National Institute of General Medical Sciences; National Science Foundation; National Cancer Institute; Université Laval; North Carolina State University; U.S. Department of Energy","keywords":"Heterotrimeric G protein; Biology; G protein; GTPase-activating protein; Arabidopsis; Arabidopsis thaliana; Guanine nucleotide exchange factor; G protein-coupled receptor; Cell biology; G beta-gamma complex; Biochemistry; RGS2; Genetics; Signal transduction; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001381596,0.0002472086,0.0002033188,0.0002193636,0.0001932653,0.0004037893,0.0001686262,0.0004166271,0.001009037],"category_scores_gemma":[0.0002329176,0.0001181978,0.0001844348,0.0002928494,0.0003004358,0.0003707812,0.0003476781,0.0004471417,0.0006370555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003312821,"about_ca_system_score_gemma":0.0002353969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007648453,"about_ca_topic_score_gemma":0.0007486459,"domain_scores_codex":[0.9998715,0.00001752433,0.000009844819,0.00004893782,0.00002900798,0.00002319808],"domain_scores_gemma":[0.9998592,0.00002285482,0.00003853532,0.00002807017,0.00001915159,0.00003217337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001029678,0.000009684781,0.001604679,0.0001263839,0.00001130528,0.000146638,0.00006008278,0.0001279065,0.9895262,0.0008746576,0.0001354166,0.007274102],"study_design_scores_gemma":[0.00004904524,0.0004215296,0.1292623,0.0001166852,0.0002846451,0.005984865,0.0004051086,0.002135244,0.7236345,0.002987356,0.1346557,0.00006298639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728379,0.0147961,0.004780191,0.0003698712,0.00007454668,0.00001663329,0.000901995,0.0002343407,0.005988368],"genre_scores_gemma":[0.9868239,0.004048304,0.005347794,0.0002222743,0.00001309447,0.00001016323,0.001408352,0.00005258173,0.002073602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001009037,"threshold_uncertainty_score":0.00337559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03849844814779917,"score_gpt":0.2593886837991604,"score_spread":0.2208902356513612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}