{"id":"W2141569270","doi":"10.1158/0008-5472.can-08-0249","title":"Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1412,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Center for Research Resources; Oregon National Primate Research Center; National Cancer Institute; Prostate Cancer Foundation; National Institutes of Health; University of Washington; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Prostate cancer; Castration; Androgen; Medicine; Prostate; Orchiectomy; Testosterone (patch); Internal medicine; Androgen deprivation therapy; Androgen receptor; CYP17A1; Cancer research; Cancer; Intracrine; Endocrinology; Oncology; Biology; Hormone; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1079303838449509,"score_gpt":0.4065856309627567,"score_spread":0.2986552471178058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}