{"id":"W2141573544","doi":"10.1091/mbc.e03-01-0018","title":"RAM: A Conserved Signaling Network That Regulates Ace2p Transcriptional Activity and Polarized Morphogenesis","year":2003,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Simon Fraser University; Queen's University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Biology; Morphogenesis; Cell biology; Cell polarity; Transcription factor; Genetic screen; Cell division; Genetics; Asymmetric cell division; Mutant; Gene; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000349057,0.0001707741,0.0001956999,0.00002658285,0.0001253998,0.0000115526,0.0002427426,0.0002388454,0.00002980311],"category_scores_gemma":[0.00005207318,0.000130567,0.000167513,0.000102646,0.0003554558,0.000001758393,0.0001239154,0.0001230774,0.000001705659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006427654,"about_ca_system_score_gemma":0.00008581275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002655268,"about_ca_topic_score_gemma":0.000007594611,"domain_scores_codex":[0.9986057,0.0004769122,0.0001441765,0.0003419507,0.0001133875,0.0003179261],"domain_scores_gemma":[0.9993898,0.00002979633,0.00008646979,0.0003506355,0.00006721497,0.00007606005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001396189,0.00004852867,0.006559892,0.00002397257,0.00007857236,0.00000146709,0.000008681561,0.0002328648,0.9924553,0.0003088324,0.0000472191,0.00009505035],"study_design_scores_gemma":[0.0006726034,0.0001374207,0.002390403,0.000009394473,0.00003239679,0.00001643181,0.00001074161,0.00005099144,0.9937184,0.001128308,0.001686062,0.0001468075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902896,0.006028536,0.002766834,0.0002003042,0.000116687,0.0002178194,0.0000253392,0.000005043373,0.0003498148],"genre_scores_gemma":[0.9974397,0.0001545957,0.001717204,0.0001680144,0.0000310823,0.00001220993,0.00002199952,0.00001931776,0.0004358189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007150135,"threshold_uncertainty_score":0.5324366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484141587870681,"score_gpt":0.2417143511046354,"score_spread":0.2268729352259286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}