{"id":"W2141607191","doi":"10.1016/j.micinf.2007.05.012","title":"Evaluation of immune responses and protection induced by A2 and nucleoside hydrolase (NH) DNA vaccines against Leishmania chagasi and Leishmania amazonensis experimental infections","year":2007,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Universidade Federal do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; McGill University","keywords":"Biology; Immune system; DNA vaccination; Antigen; Virology; Leishmania; Leishmania chagasi; Leishmania donovani; Immunization; Immunology; Microbiology; Recombinant DNA; Leishmaniasis; Visceral leishmaniasis; Parasite hosting; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004611401,0.0007827809,0.0004942163,0.0004197263,0.0002351369,0.0002881479,0.0002735354,0.0006649677,0.001956709],"category_scores_gemma":[0.0003972229,0.0002470799,0.0004040512,0.0001922781,0.0004967983,0.0003920023,0.0001861207,0.00151355,0.0003321036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002117248,"about_ca_system_score_gemma":0.0002086365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004194941,"about_ca_topic_score_gemma":0.0003153121,"domain_scores_codex":[0.9996301,0.00009659858,0.00002693867,0.00005691831,0.00004393313,0.0001455115],"domain_scores_gemma":[0.9995909,0.0001771786,0.00006637281,0.00003242362,0.00004362268,0.00008944427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004829964,0.000909295,0.0005098878,0.0001376425,0.0000188671,0.0001067651,0.0001071292,0.0001760514,0.9909877,0.0001913979,0.0000452897,0.001979982],"study_design_scores_gemma":[0.0008269665,0.01985671,0.007965137,0.00002088013,0.0001256414,0.0003391618,0.0001463067,0.001280684,0.967901,0.0002060282,0.001318312,0.00001317037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979784,0.0003491303,0.0005319965,0.00004922385,0.00004133986,0.00007847068,0.0001572758,0.00002314467,0.000791079],"genre_scores_gemma":[0.9976323,0.0003295476,0.000428422,0.00006508825,0.00004039957,0.00008848635,0.000242486,0.000006897138,0.001166482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001956709,"threshold_uncertainty_score":0.006545842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03328629838704218,"score_gpt":0.3122532232782861,"score_spread":0.2789669248912439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}