{"id":"W2141607191","doi":"10.1016/j.micinf.2007.05.012","title":"Evaluation of immune responses and protection induced by A2 and nucleoside hydrolase (NH) DNA vaccines against Leishmania chagasi and Leishmania amazonensis experimental infections","year":2007,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Universidade Federal do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; McGill University","keywords":"Biology; Immune system; DNA vaccination; Antigen; Virology; Leishmania; Leishmania chagasi; Leishmania donovani; Immunization; Immunology; Microbiology; Recombinant DNA; Leishmaniasis; Visceral leishmaniasis; Parasite hosting; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001846805,0.0002571998,0.0003930775,0.0004256702,0.0004541269,0.00008237705,0.00002149733,0.0001651615,0.00001614568],"category_scores_gemma":[0.0004384971,0.0002404887,0.00005061319,0.0002661585,0.0001899842,0.0004050352,0.0001187004,0.0002432944,0.00000151373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001491716,"about_ca_system_score_gemma":0.00004356821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001775735,"about_ca_topic_score_gemma":0.0005360639,"domain_scores_codex":[0.9982793,0.0002025713,0.0004521265,0.0004413087,0.0003424089,0.0002822537],"domain_scores_gemma":[0.9990093,0.00009508277,0.0001863683,0.0001744289,0.0003970467,0.0001378126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003517379,0.0002657258,0.03429278,0.0001240449,0.0001393609,0.000002166042,0.0006698066,8.253645e-7,0.9262305,0.000009815667,0.00009766353,0.03781552],"study_design_scores_gemma":[0.002698203,0.00146449,0.558414,0.0001538901,0.0002010507,0.0002121253,0.0005654276,0.0004346182,0.4350526,0.00002448128,0.0005911913,0.0001879162],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930747,0.004874269,0.00005740557,0.0003299748,0.0001033262,0.001225665,0.000008573982,0.00006676876,0.0002593582],"genre_scores_gemma":[0.9969705,0.002660432,0.00005417414,0.0000517027,0.00008898955,0.00006954161,0.00001355153,0.00003185857,0.00005925974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5241212,"threshold_uncertainty_score":0.9806845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03328629838704218,"score_gpt":0.3122532232782861,"score_spread":0.2789669248912439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}