{"id":"W2141680848","doi":"10.1093/hmg/dds528","title":"Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis","year":2013,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre","funders":"Medical Research Council; Healing Foundation; National Institute of Dental and Craniofacial Research; Stowers Institute for Medical Research; March of Dimes Foundation","keywords":"Biology; Pathogenesis; Enteric nervous system; Nervous system; Immunology; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005592593,0.0001106751,0.0002023078,0.0000790532,0.00003375213,0.000009766576,0.00008428896,0.00003022679,0.00001129596],"category_scores_gemma":[0.00001438418,0.00007953303,0.0000477994,0.0001110039,0.00005724067,0.00001206989,0.00007334869,0.00005363569,0.000004361566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000199147,"about_ca_system_score_gemma":0.00002569468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003458932,"about_ca_topic_score_gemma":0.00001466986,"domain_scores_codex":[0.9992139,0.00004495024,0.0002841536,0.0001376639,0.0001761664,0.0001431513],"domain_scores_gemma":[0.9996104,0.00001621002,0.00008621908,0.0001633355,0.00007514014,0.0000486871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003258626,0.00007533978,0.01812066,0.0003856188,0.00002727292,0.0001721781,0.0007380656,0.00001514419,0.9790703,0.00005303607,0.000001542621,0.001308268],"study_design_scores_gemma":[0.0003801986,0.0002716394,0.8249131,0.0001788587,0.00004817954,0.0002993026,0.0004997844,0.00005239854,0.1732591,0.00001465005,0.00001451514,0.00006823013],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985789,0.0007707613,0.00001120841,0.00005458651,0.000009928656,0.000352475,0.000001284276,0.000007854109,0.0002130052],"genre_scores_gemma":[0.9992662,0.00001550172,0.0005404783,0.00005105901,0.000008559748,0.00003794617,0.00000282266,0.00001140989,0.00006602535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8067924,"threshold_uncertainty_score":0.3243263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556885095326012,"score_gpt":0.2283961063820514,"score_spread":0.2128272554287912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}