{"id":"W2141797403","doi":"10.1099/0022-1317-83-5-973","title":"The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity","year":2002,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":347,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Capsid; Biology; Infectivity; Virology; Virus; Adeno-associated virus; Mutant; Gene; Molecular biology; Vector (molecular biology); Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001263116,0.0003992477,0.0002292338,0.0001342248,0.0001717147,0.0003857956,0.0001510254,0.0002842403,0.0006807428],"category_scores_gemma":[0.0001763292,0.0001656027,0.0002616325,0.000117137,0.0002743644,0.0003242738,0.0002145166,0.00044629,0.0002735044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003898883,"about_ca_system_score_gemma":0.0002280044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004938431,"about_ca_topic_score_gemma":0.000432549,"domain_scores_codex":[0.9998868,0.00001773288,0.000008622993,0.00002910527,0.00003502902,0.00002273896],"domain_scores_gemma":[0.9999142,0.00001875657,0.00002516781,0.00001370303,0.000007029871,0.00002112443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002216459,0.00000267875,0.00008708953,0.00001488743,0.000001725883,0.00003069631,0.000005220331,0.00003528715,0.9995041,0.00005481036,0.000005609193,0.0002357397],"study_design_scores_gemma":[0.00001114852,0.0001328157,0.005997874,0.000004149586,0.00001132257,0.0009874625,0.00002134913,0.0007413618,0.9895739,0.000124414,0.002387687,0.000006480051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950485,0.0008219168,0.003115529,0.00004951973,0.00001292547,0.0000131355,0.0001896331,0.00005062381,0.0006982226],"genre_scores_gemma":[0.9950078,0.0003595555,0.002731948,0.00002020784,0.000007815152,0.00001445004,0.0006137652,0.00001737748,0.00122703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006807428,"threshold_uncertainty_score":0.002828836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02573642794305243,"score_gpt":0.2975326513213266,"score_spread":0.2717962233782742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}