{"id":"W2141806529","doi":"10.1128/mcb.20.11.4115-4127.2000","title":"Telomere Maintenance in Telomerase-Deficient Mouse Embryonic Stem Cells: Characterization of an Amplified Telomeric DNA","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Terry Fox Research Institute; Institute of Aging","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Telomerase; Telomere; Biology; Embryonic stem cell; Cell biology; Molecular biology; Stem cell; Telomerase reverse transcriptase; Telomere-binding protein; Gene; Genetics; DNA-binding protein; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430112,0.0002015688,0.0001255617,0.0003492452,0.00009031354,0.0002321599,0.0001519907,0.000181,0.0004115206],"category_scores_gemma":[0.0001746202,0.0001105323,0.0001472535,0.0001939881,0.0001296342,0.0001648691,0.0001190784,0.0002846387,0.0002104843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009699666,"about_ca_system_score_gemma":0.00009880408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002792216,"about_ca_topic_score_gemma":0.0003417939,"domain_scores_codex":[0.9999499,0.00000485497,0.000007315464,0.00001029762,0.00002146056,0.000006144115],"domain_scores_gemma":[0.9998329,0.00002820284,0.00005134236,0.00002436655,0.00002766415,0.00003553865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001734197,0.000003850191,0.0005585245,0.000007362693,0.000001783562,0.00003375398,0.00001719804,0.00002210529,0.9986281,0.00003418393,0.000002997457,0.0006727804],"study_design_scores_gemma":[0.000008107255,0.0002260195,0.01870473,0.000005481721,0.00002343032,0.0006505566,0.00002388606,0.000748731,0.9776295,0.00008164411,0.001893195,0.000004546544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949564,0.0011254,0.003060614,0.00001781072,0.000003979566,0.00001317421,0.0003377588,0.00003228124,0.0004525056],"genre_scores_gemma":[0.9930015,0.0008245438,0.00335293,0.00002004475,0.000006276865,0.00003457812,0.001121859,0.00001598341,0.001622355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004115206,"threshold_uncertainty_score":0.001376629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008382606109708368,"score_gpt":0.220985173005501,"score_spread":0.2126025668957926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}