{"id":"W2141829289","doi":"10.1053/meta.2003.50022","title":"Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: A link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease","year":2003,"lang":"en","type":"article","venue":"Metabolism","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Multivitamin; Methylenetetrahydrofolate reductase; Hyperhomocysteinemia; Methylmalonic acid; End stage renal disease; Internal medicine; Homocysteine; Vitamin B12; Endocrinology; Medicine; Cyanocobalamin; Vitamin; Gastroenterology; Hemodialysis; Chemistry; Biochemistry; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003803161,0.0003255162,0.0009139208,0.0004716192,0.0002543282,0.0004333972,0.000436751,0.001151483,0.001662755],"category_scores_gemma":[0.001054912,0.0002139851,0.0003702011,0.0004182013,0.0004043837,0.0003844854,0.0002460149,0.000764923,0.0001721392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004530479,"about_ca_system_score_gemma":0.0004615537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001445968,"about_ca_topic_score_gemma":0.001413612,"domain_scores_codex":[0.9997663,0.00008361584,0.00003518034,0.00003317423,0.00004721669,0.00003457624],"domain_scores_gemma":[0.9995492,0.0001398607,0.0001171803,0.00006074876,0.00004699111,0.00008610654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.06476136,0.001036252,0.1196652,0.001122159,0.001649383,0.008514291,0.0004420563,0.0006496233,0.6292809,0.003319141,0.003417243,0.1661424],"study_design_scores_gemma":[0.002549265,0.009053306,0.5358876,0.0001763682,0.002447349,0.02600752,0.0005381198,0.001913342,0.3924851,0.006324224,0.02255317,0.00006461313],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736093,0.02098544,0.001019356,0.001792538,0.0001244759,0.00001267507,0.0001213293,0.0001052945,0.002229699],"genre_scores_gemma":[0.9953319,0.00259476,0.0005644598,0.0002600191,0.00007120605,0.000007103197,0.00008181584,0.00001209226,0.0010765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662755,"threshold_uncertainty_score":0.005562484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364072699831518,"score_gpt":0.2660923485619607,"score_spread":0.2524516215636455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}