{"id":"W2141873881","doi":"10.1158/0008-5472.can-08-3380","title":"LEF1 in Androgen-Independent Prostate Cancer: Regulation of Androgen Receptor Expression, Prostate Cancer Growth, and Invasion","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Center for Research Resources; U.S. Department of Defense","keywords":"LNCaP; Androgen receptor; Prostate cancer; Cancer research; Androgen; Gene knockdown; Biology; Cancer; Prostate; Internal medicine; Endocrinology; Medicine; Cell culture; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397558,0.0003471065,0.0002136305,0.0003829749,0.0002525879,0.0004421641,0.0001813704,0.0003843012,0.001273632],"category_scores_gemma":[0.0001195228,0.0001322345,0.0001909397,0.0001813261,0.0001780416,0.0002574084,0.0001285682,0.0004498837,0.000351521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004855389,"about_ca_system_score_gemma":0.0001741201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001890583,"about_ca_topic_score_gemma":0.003211536,"domain_scores_codex":[0.9999225,0.00001373598,0.000003760762,0.00001401388,0.00002808793,0.00001773947],"domain_scores_gemma":[0.9999342,0.00001529228,0.00001548671,0.000005395646,0.00001090622,0.00001875719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001706739,0.00006880575,0.002432808,0.0001060407,0.00001118701,0.0002620357,0.00004709588,0.0002183058,0.9855274,0.0002543084,0.0002925408,0.01060888],"study_design_scores_gemma":[0.00003600674,0.0003994055,0.08300312,0.00002701048,0.00003856224,0.002470186,0.0001332636,0.00272271,0.8958862,0.0003441022,0.01490794,0.00003143746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613675,0.02983712,0.004322077,0.0004155296,0.00003474385,0.00002966227,0.0004282961,0.00009886036,0.00346626],"genre_scores_gemma":[0.9853193,0.004534629,0.001714839,0.0001064644,0.0000241862,0.00002201017,0.000558619,0.00001336151,0.007706558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001890583,"threshold_uncertainty_score":0.004260719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05182841548603007,"score_gpt":0.3796057018448488,"score_spread":0.3277772863588188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}