{"id":"W2141878383","doi":"10.1152/ajpgi.90227.2008","title":"Secreted bioactive factors from <i>Bifidobacterium infantis</i> enhance epithelial cell barrier function","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":591,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Occludin; Tight junction; Barrier function; MAPK/ERK pathway; Intestinal permeability; Inflammation; Claudin; p38 mitogen-activated protein kinases; Immune system; Tumor necrosis factor alpha; Cytokine; Immunology; Chemistry; Biology; Kinase; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008504101,0.0003361909,0.000612489,0.00009062791,0.0001872926,0.000007652739,0.0002339003,0.00009296846,0.00006886164],"category_scores_gemma":[0.00004984922,0.0002723444,0.0002047106,0.000120771,0.001067677,0.00002297465,0.0001293945,0.0004092692,0.00001183654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002057605,"about_ca_system_score_gemma":0.0001944908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003960478,"about_ca_topic_score_gemma":0.000009941448,"domain_scores_codex":[0.9982243,0.0002968103,0.0004555749,0.0004791997,0.00009596143,0.0004481151],"domain_scores_gemma":[0.9984032,0.00009643826,0.000761607,0.0002356893,0.0002647244,0.0002383364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001576653,0.0001100832,0.00577179,0.0000122118,0.00008573748,0.000009271934,0.0002349757,0.00001325589,0.9916118,0.000004593695,0.0002634071,0.0003062451],"study_design_scores_gemma":[0.0007510166,0.00727587,0.7258828,0.00003678909,0.00006252201,0.0005372588,0.0004260812,0.00001202952,0.2626301,0.00006893954,0.002026635,0.0002900074],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987786,0.0002769723,0.0003840341,0.00004892389,0.0002486616,0.0000942322,0.0001176336,0.00001045089,0.00004045365],"genre_scores_gemma":[0.9961975,0.0004882956,0.001701961,0.0006511288,0.0007446381,0.000002692714,0.0001337013,0.00002676956,0.00005336682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7289817,"threshold_uncertainty_score":0.9999729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005310689703913017,"score_gpt":0.2052463381432802,"score_spread":0.1999356484393672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}