{"id":"W2141878383","doi":"10.1152/ajpgi.90227.2008","title":"Secreted bioactive factors from <i>Bifidobacterium infantis</i> enhance epithelial cell barrier function","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":591,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Occludin; Tight junction; Barrier function; MAPK/ERK pathway; Intestinal permeability; Inflammation; Claudin; p38 mitogen-activated protein kinases; Immune system; Tumor necrosis factor alpha; Cytokine; Immunology; Chemistry; Biology; Kinase; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001806462,0.0007211077,0.0003990596,0.0002072265,0.0001080015,0.0003600479,0.0001035236,0.0002504696,0.0008872646],"category_scores_gemma":[0.0002052907,0.0001107636,0.000266758,0.000138394,0.00016076,0.0001703753,0.000219504,0.0004876851,0.0002817868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002289395,"about_ca_system_score_gemma":0.0001581359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004763506,"about_ca_topic_score_gemma":0.0007624261,"domain_scores_codex":[0.9998497,0.00003639932,0.00001202729,0.0000177149,0.00003724436,0.00004694207],"domain_scores_gemma":[0.9998642,0.00001502181,0.00005142355,0.000008541396,0.00002175202,0.00003914949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002869478,0.0000352817,0.0003184266,0.00007013594,0.00000589959,0.00003728083,0.000006904539,0.00001951222,0.9959644,0.00001196762,0.0000406892,0.003202426],"study_design_scores_gemma":[0.00007406494,0.002787743,0.01707953,0.00003574456,0.00005920264,0.000435868,0.00005004034,0.0002781498,0.9752847,0.00002604483,0.003881375,0.000007623379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907782,0.006489058,0.001287872,0.0001648258,0.00004179943,0.00003024776,0.0002398157,0.00007737188,0.0008907406],"genre_scores_gemma":[0.9910249,0.003663946,0.003533654,0.000114115,0.00004732856,0.00003191057,0.000682614,0.00002465005,0.0008769507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008872646,"threshold_uncertainty_score":0.002968252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005310689703913017,"score_gpt":0.2052463381432802,"score_spread":0.1999356484393672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}