{"id":"W2141880963","doi":"10.1002/elan.201500138","title":"Electroanalysis of Natural Compounds as Copper Chelating Agents for Alzheimer’s Disease Therapy","year":2015,"lang":"en","type":"article","venue":"Electroanalysis","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Alzheimer Society","keywords":"Clioquinol; Baicalein; Chelation; Chemistry; Chelation therapy; Differential pulse voltammetry; Copper; Resveratrol; Pharmacology; Nuclear chemistry; Cyclic voltammetry; Electrochemistry; Biochemistry; Inorganic chemistry; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002127479,0.0002569748,0.0001424158,0.0003307305,0.0000884941,0.0001784541,0.0001672808,0.0002602269,0.000669368],"category_scores_gemma":[0.0001710335,0.00008603436,0.0001327601,0.0001483525,0.0001352355,0.0001684358,0.0001208418,0.0002088893,0.0001505704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001649592,"about_ca_system_score_gemma":0.0001333371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003789371,"about_ca_topic_score_gemma":0.0007902066,"domain_scores_codex":[0.9999205,0.00002717722,0.000005420328,0.00001391246,0.00002248844,0.00001057664],"domain_scores_gemma":[0.9999435,0.00001475685,0.00001028194,0.000003254628,0.00002221743,0.000006091322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008298577,0.00002008032,0.0002034997,0.00014717,0.00001289599,0.00003618821,0.00001369432,0.00007660838,0.9915395,0.000137371,0.0001325071,0.007597467],"study_design_scores_gemma":[0.00001493415,0.0002655421,0.001571203,0.00002148213,0.00002979863,0.0001745502,0.00002929636,0.001272362,0.9928465,0.0001102966,0.003659789,0.000004272144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8954399,0.05639653,0.03844956,0.0007214622,0.0002258472,0.0001495107,0.0003418123,0.0002267766,0.008048551],"genre_scores_gemma":[0.9779794,0.006487482,0.01238815,0.0002158701,0.00003020314,0.00005894136,0.0001169706,0.000009355409,0.002713643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000669368,"threshold_uncertainty_score":0.002239227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06955650287480752,"score_gpt":0.3415223727359507,"score_spread":0.2719658698611432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}