{"id":"W2141881379","doi":"10.1586/14760584.1.1.85","title":"Technological advances to increase immunogenicity of DNA vaccines","year":2002,"lang":"en","type":"review","venue":"Expert Review of Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Supratek Pharma (Canada)","funders":"","keywords":"Immunogenicity; DNA vaccination; Immune system; Immunology; Malaria; Infectious disease (medical specialty); Medicine; Virology; Antigen; Disease; Biology; Immunization","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008050553,0.0009532529,0.005858853,0.0005173904,0.0001270269,0.000008234198,0.001645404,0.0008039742,0.003593539],"category_scores_gemma":[0.00150843,0.0006262434,0.001670677,0.00108294,0.0002397138,0.0001534179,0.0004338906,0.0005445143,0.0004366582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006254543,"about_ca_system_score_gemma":0.000152417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005560647,"about_ca_topic_score_gemma":0.0000017673,"domain_scores_codex":[0.9948664,0.001153551,0.002615948,0.0006900361,0.0001115364,0.000562474],"domain_scores_gemma":[0.9956588,0.0009172987,0.00151209,0.001575583,0.0002971759,0.00003907166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001338894,0.0003163872,0.000002256638,0.04687496,0.0006367686,0.000004061637,0.00004111113,1.747109e-8,0.002689904,0.0000946108,0.008237518,0.9409685],"study_design_scores_gemma":[0.0004119078,0.0003709634,0.000003974363,0.1234442,0.0004305892,0.0002371067,0.00002504722,1.383913e-8,0.004266785,0.000006208489,0.8702784,0.0005248095],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004874682,0.9967076,0.00002363069,0.0001287614,0.0006965275,0.00186457,0.0001064281,0.000112753,0.0003110143],"genre_scores_gemma":[0.0000218506,0.9974635,0.0002737551,0.0002797197,0.00006501331,0.0004078113,0.0001538268,0.00007574612,0.001258789],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9404437,"threshold_uncertainty_score":0.9996189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02525096984866707,"score_gpt":0.3369463403100737,"score_spread":0.3116953704614066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}