{"id":"W2141913072","doi":"10.1016/j.ymthe.2004.05.026","title":"Potential Utility of BimS as a Novel Apoptotic Therapeutic Molecule","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"","keywords":"Apoptosis; Biology; Cancer research; Genetic enhancement; Inhibitor of apoptosis; In vivo; Adeno-associated virus; Molecular biology; Immunology; Programmed cell death; Recombinant DNA; Gene; Vector (molecular biology); Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003536399,0.0003280804,0.0002936498,0.0001188687,0.00009210445,0.00003264217,0.0005811188,0.0002369636,0.0001627857],"category_scores_gemma":[0.00003056566,0.0003121193,0.000335368,0.0002975164,0.0002637566,0.000005996434,0.0001040176,0.000190597,0.00004747788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002437515,"about_ca_system_score_gemma":0.0003319441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008083018,"about_ca_topic_score_gemma":0.00001672008,"domain_scores_codex":[0.9978517,0.0001394069,0.0003529098,0.0006111912,0.000515467,0.0005292977],"domain_scores_gemma":[0.9985144,0.000007147067,0.0001214908,0.0009995229,0.0001990555,0.0001584268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002459255,0.0005398609,0.00005036405,0.00001318006,0.0002825667,0.00001879144,0.00006003667,0.0007477951,0.9894053,0.0002651065,0.00001426066,0.006143453],"study_design_scores_gemma":[0.003577279,0.003625163,0.0004459693,0.00001274819,0.00001729852,0.00003388137,0.00003353171,0.0000750339,0.9893659,0.001615951,0.0008833951,0.0003138887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660327,0.003802379,0.02829282,0.0003623439,0.00009606223,0.0005462912,0.00002039754,0.00003088614,0.0008161278],"genre_scores_gemma":[0.9972764,0.0004536756,0.0006140494,0.001236432,0.00007810555,0.00004877532,0.00007369051,0.00008497893,0.0001339084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03124369,"threshold_uncertainty_score":0.9999331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01841421016180691,"score_gpt":0.2971242115500142,"score_spread":0.2787100013882073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}