{"id":"W2141913072","doi":"10.1016/j.ymthe.2004.05.026","title":"Potential Utility of BimS as a Novel Apoptotic Therapeutic Molecule","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"","keywords":"Apoptosis; Biology; Cancer research; Genetic enhancement; Inhibitor of apoptosis; In vivo; Adeno-associated virus; Molecular biology; Immunology; Programmed cell death; Recombinant DNA; Gene; Vector (molecular biology); Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008246935,0.0003655529,0.0003146677,0.0004211965,0.0004106285,0.0005072022,0.0005774351,0.0006170136,0.002170393],"category_scores_gemma":[0.0002891005,0.0001405817,0.0002694442,0.0001676929,0.0004606219,0.0005939589,0.0003150913,0.0008759755,0.0004611415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005032627,"about_ca_system_score_gemma":0.0004345006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002216971,"about_ca_topic_score_gemma":0.0002077296,"domain_scores_codex":[0.9998719,0.0000488828,0.000004440025,0.0000161795,0.00002250828,0.00003617908],"domain_scores_gemma":[0.9999229,0.00002684298,0.000008340468,0.000008818494,0.00001124783,0.00002185277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00311576,0.0007573747,0.000747197,0.0004549658,0.00005195607,0.0005941829,0.0001481818,0.001761419,0.8829662,0.04297354,0.002243411,0.06418582],"study_design_scores_gemma":[0.0006630944,0.003813313,0.001394,0.00005130517,0.0001012386,0.001575875,0.00008371926,0.004814077,0.9229342,0.008662849,0.05587536,0.00003095867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8450191,0.05230325,0.05769665,0.005338283,0.0008257641,0.0003795464,0.0005464311,0.0006565815,0.03723441],"genre_scores_gemma":[0.962058,0.008824883,0.01658055,0.0005637668,0.0001415584,0.0001930583,0.0003775222,0.00003924911,0.01122142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002170393,"threshold_uncertainty_score":0.00726068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01841421016180691,"score_gpt":0.2971242115500142,"score_spread":0.2787100013882073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}