{"id":"W2141926462","doi":"10.1126/science.288.5466.665","title":"Extension of Cell Life-Span and Telomere Length in Animals Cloned from Senescent Somatic Cells","year":2000,"lang":"en","type":"article","venue":"Science","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":468,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Terry Fox Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute on Aging","keywords":"Telomere; Somatic cell; Biology; Cloning (programming); Population; Senescence; Genetics; Life span; Southern blot; Gene; Molecular biology; Andrology; Cell biology; Evolutionary biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004023205,0.0001628216,0.0001507257,0.000321477,0.0001821115,0.0002681081,0.000198834,0.000257551,0.0006943108],"category_scores_gemma":[0.000559867,0.00009903707,0.0001514865,0.0001124044,0.0002908003,0.0002034039,0.0002988082,0.0004556889,0.0001929322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001940514,"about_ca_system_score_gemma":0.0001716414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004911207,"about_ca_topic_score_gemma":0.0006303726,"domain_scores_codex":[0.9998066,0.00003302922,0.00002228135,0.00003949455,0.00005689167,0.0000417409],"domain_scores_gemma":[0.9993961,0.0001716967,0.0001556771,0.00007081184,0.00008625344,0.0001193843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005807425,0.00001690737,0.003046301,0.0000146103,0.000006081838,0.0001387705,0.00008885483,0.00002737043,0.9943587,0.00009136571,0.000009161162,0.002143809],"study_design_scores_gemma":[0.0000258453,0.001563285,0.07282066,0.00002297781,0.00009648039,0.003459113,0.0002095557,0.0007629779,0.9164022,0.0002230926,0.004396216,0.00001764488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964105,0.0004934201,0.002715925,0.00002308434,0.000007445497,0.00001032732,0.0000670325,0.00001500852,0.0002571535],"genre_scores_gemma":[0.9949269,0.0005585703,0.002408244,0.00002181722,0.000006420566,0.00002037776,0.0005296846,0.00001204685,0.001515873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006943108,"threshold_uncertainty_score":0.002322674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009900820868093232,"score_gpt":0.2466345255614412,"score_spread":0.236733704693348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}