{"id":"W2142000487","doi":"10.1128/mcb.26.8.2947-2954.2006","title":"Subcellular Targeting of p33 <sup>ING1b</sup> by Phosphorylation-Dependent 14-3-3 Binding Regulates p21 <sup>WAF1</sup> Expression","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Heritage Medical Research Clinic","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Biology; Subcellular localization; Ectopic expression; Nuclear localization sequence; Chromatin; Transcription factor; Cell biology; Phosphorylation; DNA damage; DNA-binding protein; Cyclin D1; Cytoplasm; RNA splicing; DNA repair; Homeobox; Molecular biology; Gene; Genetics; DNA; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004499459,0.0004913584,0.0004793883,0.0001680489,0.000282998,0.00005641592,0.0003712008,0.0006484704,0.0001419452],"category_scores_gemma":[0.0001438811,0.000491024,0.0002715381,0.0001927751,0.0002839296,0.00002046643,0.0003416498,0.0003162675,0.00002421664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004338085,"about_ca_system_score_gemma":0.00006330593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002667683,"about_ca_topic_score_gemma":0.000004664269,"domain_scores_codex":[0.996987,0.0003437635,0.000765674,0.0009909455,0.0002508311,0.0006617944],"domain_scores_gemma":[0.9985822,0.00004942561,0.0003596757,0.0006557764,0.0001996004,0.0001533093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009630066,0.0001440364,0.003517932,0.00004996427,0.00009990632,0.00002330932,0.00007703373,0.002057626,0.9913068,0.0002779836,0.001915505,0.0004335927],"study_design_scores_gemma":[0.0008743817,0.0002913255,0.00003100067,0.00005207105,0.00006524179,0.0000330919,0.0002110976,0.001199528,0.9744923,0.0005121317,0.02173493,0.0005029103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9624444,0.01267796,0.02331374,0.0001056002,0.000123571,0.0004549072,0.0001112448,0.00004596331,0.0007226685],"genre_scores_gemma":[0.9938114,0.0002232879,0.001853604,0.0000839053,0.0001978628,0.00006512117,0.002433213,0.00008547933,0.001246138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03136704,"threshold_uncertainty_score":0.9997541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003707032288827701,"score_gpt":0.2077538964918203,"score_spread":0.2040468642029926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}