{"id":"W2142000487","doi":"10.1128/mcb.26.8.2947-2954.2006","title":"Subcellular Targeting of p33 <sup>ING1b</sup> by Phosphorylation-Dependent 14-3-3 Binding Regulates p21 <sup>WAF1</sup> Expression","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Heritage Medical Research Clinic","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Biology; Subcellular localization; Ectopic expression; Nuclear localization sequence; Chromatin; Transcription factor; Cell biology; Phosphorylation; DNA damage; DNA-binding protein; Cyclin D1; Cytoplasm; RNA splicing; DNA repair; Homeobox; Molecular biology; Gene; Genetics; DNA; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007677454,0.0002472845,0.0001475246,0.0001315926,0.0002476396,0.0002938176,0.0001614436,0.0001625272,0.001427321],"category_scores_gemma":[0.00008117723,0.0001432666,0.0002294061,0.0001143797,0.0002024537,0.0001410315,0.000197398,0.000510238,0.0007519173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004269156,"about_ca_system_score_gemma":0.0002502657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001535223,"about_ca_topic_score_gemma":0.001951476,"domain_scores_codex":[0.9999065,0.00001025746,0.00000615519,0.00001782863,0.00002433921,0.00003487183],"domain_scores_gemma":[0.9999338,0.000007265745,0.00002213584,0.000006209691,0.000008333046,0.00002220099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008830333,0.00001741521,0.0002697543,0.00001929908,0.00000260046,0.00003713002,0.00001068325,0.00005757263,0.9987909,0.0001021396,0.00007656738,0.0005276178],"study_design_scores_gemma":[0.00001204991,0.00008148695,0.01742782,0.000006708858,0.00001003889,0.0002433486,0.00004392677,0.002950052,0.9758546,0.00008395463,0.003280284,0.000005725834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952867,0.0008990353,0.001947212,0.0001474101,0.0000207547,0.00001583718,0.0002899966,0.00009482085,0.001298237],"genre_scores_gemma":[0.9958236,0.0004292484,0.001114557,0.00005050169,0.000004967455,0.00002131954,0.000490237,0.00002764635,0.002037877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001535223,"threshold_uncertainty_score":0.004774868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003707032288827701,"score_gpt":0.2077538964918203,"score_spread":0.2040468642029926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}