{"id":"W2142049114","doi":"10.1089/104303404772679986","title":"Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells","year":2004,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa; McMaster University","funders":"","keywords":"Transduction (biophysics); Biology; C2C12; RGD motif; Viral vector; Reporter gene; Adenoviridae; Molecular biology; Genetic enhancement; Cell culture; Cell biology; Myocyte; Receptor; Virology; Gene; Gene expression; Integrin; Myogenesis; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004463511,0.0005277852,0.0003654196,0.0002306289,0.0001457301,0.0003699877,0.000338385,0.0002800072,0.00113257],"category_scores_gemma":[0.0001468579,0.0002082437,0.0002581321,0.0001837257,0.0002033486,0.0002961524,0.0002778542,0.0008156259,0.0005907807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002762227,"about_ca_system_score_gemma":0.0003288494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005476679,"about_ca_topic_score_gemma":0.0009494798,"domain_scores_codex":[0.9997681,0.00002693237,0.00003635677,0.00005748153,0.00007503886,0.00003607848],"domain_scores_gemma":[0.9998342,0.00003406819,0.00003938941,0.00002311227,0.00003008804,0.00003921935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001680484,0.00001284225,0.00004497793,0.00002182893,0.000001507645,0.000017885,0.00001197769,0.00002617085,0.9989599,0.00007439392,0.00001408874,0.0007975582],"study_design_scores_gemma":[0.000009632538,0.0001582948,0.0009081244,0.000004092556,0.00001099446,0.0001991804,0.00001168656,0.0006887089,0.9950719,0.00002501487,0.002907269,0.000005008479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9246752,0.002449839,0.06839845,0.000108565,0.0001248086,0.0003064137,0.0008218659,0.0003687922,0.002746108],"genre_scores_gemma":[0.8960574,0.003158622,0.0852323,0.00008862532,0.00003746332,0.0001890978,0.002240782,0.0001647635,0.01283105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00113257,"threshold_uncertainty_score":0.003788829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03154301907415948,"score_gpt":0.29853788963038,"score_spread":0.2669948705562206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}