{"id":"W2142049114","doi":"10.1089/104303404772679986","title":"Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells","year":2004,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa; McMaster University","funders":"","keywords":"Transduction (biophysics); Biology; C2C12; RGD motif; Viral vector; Reporter gene; Adenoviridae; Molecular biology; Genetic enhancement; Cell culture; Cell biology; Myocyte; Receptor; Virology; Gene; Gene expression; Integrin; Myogenesis; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002424123,0.0001843998,0.0001950365,0.00006648637,0.0001481674,0.00002400275,0.0001575523,0.0001646892,0.0000276732],"category_scores_gemma":[0.000004083829,0.0001777017,0.00009194377,0.00005924397,0.00008313142,0.000006551398,0.00002455495,0.00009297602,0.000001054201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003630456,"about_ca_system_score_gemma":0.0001065135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002943273,"about_ca_topic_score_gemma":0.00008383446,"domain_scores_codex":[0.9989625,0.00004801299,0.0002256872,0.0003600788,0.0001157871,0.0002879972],"domain_scores_gemma":[0.9994916,0.000007667329,0.00008202735,0.0002571578,0.0001016564,0.00005983906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001915354,0.0000461273,0.000005257778,0.00002211915,0.00008954132,6.356088e-7,0.0004694875,0.0003572225,0.9894345,0.00003322242,0.00001242629,0.007614097],"study_design_scores_gemma":[0.003596484,0.003365469,0.0002896754,0.0000120909,0.000008148412,0.000003997025,0.0001052526,0.00001365158,0.9913088,0.0003796437,0.0007052483,0.00021156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952793,0.001870855,0.001986225,0.0001267656,0.00007149881,0.0005868318,0.00003096427,0.00001652886,0.00003102763],"genre_scores_gemma":[0.9973897,0.0005397826,0.001288554,0.0001648059,0.0002074536,0.00006348528,0.00009298378,0.00005063463,0.0002026078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007402537,"threshold_uncertainty_score":0.7246467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03154301907415948,"score_gpt":0.29853788963038,"score_spread":0.2669948705562206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}