{"id":"W2142104298","doi":"10.3174/ajnr.a3709","title":"Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T","year":2013,"lang":"en","type":"article","venue":"American Journal of Neuroradiology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; National Research Council Institute for Biodiagnostics; Dalhousie University; Nova Scotia Health Authority; Izaak Walton Killam Health Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute on Aging; National Research Council Canada; Foundation for the National Institutes of Health; Tianjin Medical University; Dalhousie University; University of California, San Francisco; University of California, San Diego; National Natural Science Foundation of China; University of California, Los Angeles; Dalhousie Medical Research Foundation; Northern California Institute for Research and Education; National Institutes of Health; Canadian Institutes of Health Research; National Science Foundation","keywords":"Medicine; Atrophy; Lesion; Brain aging; Alzheimer's disease; Pathology; Magnetic resonance imaging; Degenerative disease; Neuroscience; Disease; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00272036,0.0004635522,0.0003467539,0.002520621,0.0002613595,0.0005739286,0.0003458079,0.0003200779,0.0006811438],"category_scores_gemma":[0.004056809,0.0001319974,0.0003563564,0.0008795387,0.0004143345,0.0006685998,0.0005900203,0.0002771092,0.0001241419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003095802,"about_ca_system_score_gemma":0.000279627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519433,"about_ca_topic_score_gemma":0.004188494,"domain_scores_codex":[0.9993581,0.0001674331,0.0001123091,0.0001215254,0.0002038257,0.000036729],"domain_scores_gemma":[0.9975951,0.0003856063,0.001120488,0.0001594392,0.0005289783,0.0002103386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006952264,0.0001063674,0.9739381,0.00006702657,0.0003713844,0.00008863967,0.000330153,0.0002489009,0.004206212,0.00005555627,0.0001579662,0.01973434],"study_design_scores_gemma":[0.00001078898,0.0002857928,0.9968176,0.00001200918,0.00005677501,0.0005141367,0.0001149303,0.0008324612,0.001138891,0.00007730765,0.0001298214,0.000009582382],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983969,0.0002955935,0.0007371288,0.00001118701,0.00000455695,0.00002460348,0.00009677947,0.00001212637,0.0004211205],"genre_scores_gemma":[0.9976477,0.00009673718,0.001901858,0.000008982021,0.000008020164,0.0000208062,0.0001686718,0.000005273811,0.0001420187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00272036,"threshold_uncertainty_score":0.01438677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07477189910243667,"score_gpt":0.3670695139258433,"score_spread":0.2922976148234067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}