{"id":"W2142118427","doi":"10.1074/jbc.m112.401240","title":"Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":278,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"NMDA receptor; Phosphorylation; Postsynaptic potential; FYN; Tau protein; Endogeny; Cell biology; Biology; Receptor; Postsynaptic density; Neuroscience; Chemistry; Biochemistry; Alzheimer's disease; Internal medicine; Proto-oncogene tyrosine-protein kinase Src; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001474358,0.0002926055,0.0003025044,0.0002430949,0.0003129513,0.000505738,0.0001708037,0.0002016932,0.001171983],"category_scores_gemma":[0.0002206524,0.0001561822,0.0003351564,0.0001529933,0.0002683382,0.0002879556,0.0003144808,0.0003414204,0.0004797648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004430837,"about_ca_system_score_gemma":0.0001859332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000473053,"about_ca_topic_score_gemma":0.0007207082,"domain_scores_codex":[0.9997885,0.00003105398,0.00002098814,0.00004642632,0.00005758552,0.00005547725],"domain_scores_gemma":[0.9998837,0.00001065582,0.00004600817,0.000009408452,0.00002047178,0.00002977295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001598212,0.00003612215,0.0005998082,0.00003790521,0.00001084441,0.0001954931,0.00002598555,0.00001782253,0.9976587,0.0001244069,0.00004954113,0.001083601],"study_design_scores_gemma":[0.00003956346,0.0002494938,0.05969541,0.00001767566,0.00004259983,0.000936837,0.0001027401,0.001101509,0.9352415,0.0002578578,0.002304048,0.00001080646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900766,0.005791097,0.002010162,0.00009832405,0.00005232773,0.00001414226,0.000123513,0.00005636198,0.001777429],"genre_scores_gemma":[0.995106,0.001816702,0.001098356,0.00003597372,0.00002161191,0.00002654991,0.0001780333,0.00001512773,0.001701636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001171983,"threshold_uncertainty_score":0.003920674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03959246369258746,"score_gpt":0.2903352273145033,"score_spread":0.2507427636219159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}