{"id":"W2142197552","doi":"10.1016/j.ydbio.2009.11.031","title":"Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome","year":2009,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Centre National de la Recherche Scientifique; Muscular Dystrophy Association","keywords":"Myotome; Biology; Myogenesis; Myocyte; Gene; Chromatin immunoprecipitation; MYF5; Regulatory sequence; Transcription factor; Transactivation; Regulation of gene expression; Cell biology; Gene expression; Genetics; Myogenin; Promoter; Somite; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172396,0.000185828,0.0001497031,0.00004232445,0.0001598154,0.00001634677,0.000323964,0.0001899084,0.00001745124],"category_scores_gemma":[0.0000283459,0.0001135523,0.00003489346,0.0001522413,0.0001287815,0.000006610836,0.0001915516,0.0001352481,0.00001249479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001451506,"about_ca_system_score_gemma":0.0000567515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001589505,"about_ca_topic_score_gemma":0.00001183865,"domain_scores_codex":[0.9988757,0.0001411192,0.0001849477,0.0004124554,0.00006194356,0.0003237878],"domain_scores_gemma":[0.9996085,0.00002294606,0.00005004579,0.0002394194,0.00002364027,0.0000554445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002159493,0.0001232099,0.003623402,0.000003797755,0.0000141974,0.000002122488,0.0004385044,0.000003126189,0.9632918,0.0000108574,0.001730618,0.03054239],"study_design_scores_gemma":[0.0006259494,0.0007674848,0.2637494,0.000005718502,0.000005392894,0.00001690486,0.000475925,0.000003395683,0.7042549,0.0002934812,0.02952094,0.0002805194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968755,0.0003936212,0.00003878397,0.001419669,0.00006099792,0.0005188647,0.00001308571,0.00001636907,0.0006631459],"genre_scores_gemma":[0.9861444,0.0002692068,0.001915706,0.01107226,0.00006602941,0.00008282434,0.0003485996,0.00000986815,0.00009110847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.260126,"threshold_uncertainty_score":0.4630527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009950389110141945,"score_gpt":0.258110728203088,"score_spread":0.248160339092946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}