{"id":"W2142287897","doi":"10.1110/ps.9.10.2043","title":"For the record: A logical sequence search for S100B target proteins","year":2000,"lang":"en","type":"article","venue":"Protein Science","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Desmin; Intermediate filament; Tubulin; Vimentin; Biology; Glial fibrillary acidic protein; Consensus sequence; Conserved sequence; Sequence (biology); Peptide sequence; Neurofilament; Calcium-binding protein; Cytoskeleton; Cell biology; Biochemistry; Chemistry; Microtubule; Calcium; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001218125,0.000150053,0.0001145336,0.0000320959,0.0006956464,0.0001189905,0.0008589854,0.00008812868,0.0001459111],"category_scores_gemma":[0.0002712626,0.00009769122,0.0001125822,0.000307084,0.000687481,0.00001550246,0.0001030087,0.00009444672,0.00001904468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002219129,"about_ca_system_score_gemma":0.0003233936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004545401,"about_ca_topic_score_gemma":0.00001444529,"domain_scores_codex":[0.9983088,0.00003042629,0.0001861593,0.0006221116,0.0002725265,0.0005799901],"domain_scores_gemma":[0.9991107,0.00002906621,0.00004446355,0.0004838229,0.0002165855,0.000115343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001769302,0.00005155028,0.00007490266,0.00002222389,0.000006874383,6.203121e-7,0.00004318608,0.000082723,0.9361748,0.001309625,0.0002303907,0.06182623],"study_design_scores_gemma":[0.0004002359,0.0008877156,0.0001384991,0.000019094,0.000004135318,0.000007595123,0.00005009352,0.002739493,0.8058451,0.001380732,0.1883197,0.0002075724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8696727,0.000598517,0.116459,0.002869779,0.0001233361,0.008138584,0.0001155895,0.00004519867,0.00197733],"genre_scores_gemma":[0.9427498,0.00003733586,0.04785047,0.0005009121,0.0003992659,0.003270762,0.00001496286,0.00002075866,0.005155711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1880893,"threshold_uncertainty_score":0.535042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.048000281730809,"score_gpt":0.3246361488923147,"score_spread":0.2766358671615057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}