{"id":"W2142305450","doi":"10.1093/nar/gkq554","title":"Alternative splicing of CD200 is regulated by an exonic splicing enhancer and SF2/ASF","year":2010,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Toronto General Hospital; Hospital for Sick Children; University of Toronto","funders":"Heart and Stroke Foundation of Canada","keywords":"RNA splicing; Biology; Exon; Alternative splicing; Exonic splicing enhancer; Enhancer; Gene knockdown; Splicing factor; SR protein; Molecular biology; Electrophoretic mobility shift assay; RNA-binding protein; Exon skipping; Cell biology; RNA; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002026493,0.0004005588,0.0002457893,0.0002665752,0.0001622103,0.000297029,0.0001353535,0.0002574658,0.0009264647],"category_scores_gemma":[0.0001487136,0.0001542111,0.000275381,0.0001518167,0.0002406642,0.0001525746,0.0001477942,0.0003424256,0.0004946888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003906231,"about_ca_system_score_gemma":0.0001817145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008622823,"about_ca_topic_score_gemma":0.0009852838,"domain_scores_codex":[0.9997864,0.0000342305,0.00001468025,0.00006677572,0.0000619403,0.00003598891],"domain_scores_gemma":[0.9998866,0.00002100955,0.00003380016,0.00001225988,0.00001821298,0.0000279794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006368757,0.000008247826,0.0001964424,0.00000992185,0.000001931692,0.00006011433,0.00001003156,0.00002321857,0.9987742,0.00009430005,0.00003552466,0.0007222734],"study_design_scores_gemma":[0.00003747726,0.0001101406,0.01310817,0.000007745383,0.000013514,0.0006955125,0.00004447446,0.002735756,0.9773178,0.0001710244,0.005750084,0.000008171515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841856,0.002450841,0.01069608,0.0001477477,0.00006255416,0.00002547616,0.000378194,0.0001702868,0.00188325],"genre_scores_gemma":[0.987253,0.0007289922,0.006850256,0.00007992913,0.00002675968,0.00003069552,0.001043656,0.0000264342,0.003960203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009264647,"threshold_uncertainty_score":0.003099322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02276856873494963,"score_gpt":0.350665501615689,"score_spread":0.3278969328807394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}