{"id":"W2142315632","doi":"10.1158/1078-0432.ccr-03-0634","title":"Phase I Study of Concomitant Chemoradiotherapy with Paclitaxel, Fluorouracil, Gemcitabine, and Twice-Daily Radiation in Patients with Poor-Prognosis Cancer of the Head and Neck","year":2004,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute","keywords":"Mucositis; Medicine; Gemcitabine; Concomitant; Antimetabolite; Fluorouracil; Chemoradiotherapy; Regimen; Neutropenia; Internal medicine; Radiation therapy; Head and neck cancer; Chemotherapy; Surgery; Gastroenterology; Phases of clinical research; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001138271,0.001033927,0.001553238,0.0002095396,0.0003515973,0.0005357778,0.0006913856,0.0006758856,0.002294385],"category_scores_gemma":[0.0008359589,0.0004011641,0.0007842978,0.0002884351,0.0009335308,0.0004918081,0.0002922406,0.001707492,0.0004608099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007459063,"about_ca_system_score_gemma":0.00167188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008580282,"about_ca_topic_score_gemma":0.002157183,"domain_scores_codex":[0.9995784,0.0002188274,0.00002464087,0.00006225254,0.00003590713,0.00007991365],"domain_scores_gemma":[0.9990938,0.0001535336,0.0001730997,0.00006781669,0.00003782279,0.0004739471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.755922,0.07756065,0.02502564,0.0007036206,0.001406482,0.0002637437,0.0004488881,0.002325258,0.04610244,0.0001609028,0.002019743,0.08806068],"study_design_scores_gemma":[0.360895,0.6101169,0.01942518,0.0000333243,0.0005670612,0.0003313153,0.00006764477,0.0008538694,0.005594416,0.00007279572,0.002025853,0.00001665344],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971879,0.0009456642,0.0002554408,0.0001242619,0.00003632587,0.0008469869,0.0001557378,0.00002702783,0.0004206176],"genre_scores_gemma":[0.9937487,0.0009269448,0.001556206,0.0003217753,0.0001251204,0.00173219,0.000857959,0.00001212193,0.000719092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002294385,"threshold_uncertainty_score":0.007675529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1034947615815202,"score_gpt":0.4728574492912854,"score_spread":0.3693626877097652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}