{"id":"W2142398467","doi":"10.1136/thorax.58.8.703","title":"Polymorphisms in the  2 adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers","year":2003,"lang":"en","type":"article","venue":"Thorax","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Research (Canada)","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Medicine; Bronchodilator; Bronchial hyperresponsiveness; Internal medicine; Odds ratio; Lung function; Lung; Asthma; Haplotype; Loss of heterozygosity; Gastroenterology; Cardiology; Allele; Endocrinology; Respiratory disease; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009324397,0.0002312953,0.0002685364,0.0005229738,0.000158247,0.0003221203,0.0002422407,0.0005866538,0.001194599],"category_scores_gemma":[0.002277473,0.0002216764,0.0002878573,0.00036394,0.0002709703,0.0001781873,0.000171081,0.0004284906,0.0001624733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132553,"about_ca_system_score_gemma":0.0001365393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001704361,"about_ca_topic_score_gemma":0.001392312,"domain_scores_codex":[0.9996635,0.0001369838,0.00003189222,0.00007382789,0.0000556234,0.00003809798],"domain_scores_gemma":[0.9981067,0.0007264503,0.000778805,0.00008189961,0.00007696744,0.0002291514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001523603,0.00001921292,0.9986331,0.000003856377,0.00004689094,0.00004754682,0.00002242742,0.00003196013,0.0005929459,0.000007405609,0.0000161314,0.0004261211],"study_design_scores_gemma":[0.000006563868,0.00008870557,0.9993184,0.000002744826,0.00002675976,0.0002515265,0.0000191591,0.0001581043,0.00008213773,0.00001663824,0.0000276327,0.000001627418],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996254,0.0001762507,0.00004484042,0.00001602824,0.000001871142,0.000002117549,0.00005221216,0.000001751867,0.00007942339],"genre_scores_gemma":[0.9996532,0.00006626215,0.00006527455,0.00001100497,0.000008457072,0.000003623493,0.00008769488,0.000001338547,0.0001030456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001704361,"threshold_uncertainty_score":0.004931271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241445215438865,"score_gpt":0.2681267225025445,"score_spread":0.2557122703481559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}