{"id":"W2142458040","doi":"10.1139/cjm-2015-0166","title":"Creating a customized intracellular niche: subversion of host cell signaling by <i>Legionella</i> type IV secretion system effectors","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; Medical Research Council; Deutscher Akademischer Austauschdienst; Imperial College London; Wellcome Trust","keywords":"Effector; Legionella pneumophila; Biology; Secretion; Legionella; Cell biology; Vacuole; Intracellular parasite; Intracellular; Microbiology; Genetics; Bacteria; Cytoplasm; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007609177,0.0001296549,0.0002986307,0.0001891176,0.00004870954,0.00001202719,0.0002350422,0.0002587274,0.000009464941],"category_scores_gemma":[0.0001303413,0.0001178459,0.00009086407,0.0001648757,0.0001224052,0.00000614353,0.00002622236,0.0002205781,0.000006571318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001502136,"about_ca_system_score_gemma":0.001012536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00233716,"about_ca_topic_score_gemma":0.0009632884,"domain_scores_codex":[0.9987866,0.0002656098,0.0003920739,0.0001719036,0.00005937545,0.0003244398],"domain_scores_gemma":[0.9988899,0.00003611878,0.0002667949,0.0001369226,0.000329605,0.0003406139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002869273,0.00001502495,0.006000508,0.0000493789,0.00002581972,0.00005565042,0.0001501454,0.0001297973,0.9875392,0.00000516301,0.005703835,0.00003860635],"study_design_scores_gemma":[0.002887445,0.0008549227,0.00003585055,0.0001311497,0.00002838247,0.0003243379,0.001081457,0.0001068432,0.9805238,0.000003380425,0.01384603,0.0001764232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994447,0.004545187,0.0001413236,0.00008216912,0.0003233931,0.0001269542,0.00002157555,0.000001734736,0.0003106641],"genre_scores_gemma":[0.9993988,0.00006544647,0.0001128967,0.00004421406,0.0001368843,8.763806e-7,0.00008434224,0.00001687331,0.0001396151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008142198,"threshold_uncertainty_score":0.4805618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008534242214512674,"score_gpt":0.2109479356504862,"score_spread":0.2024136934359735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}