{"id":"W2142465751","doi":"10.1046/j.1462-5822.2001.00119.x","title":"Cholera toxin and Escherichia coli enterotoxin B-subunits inhibit macrophage-mediated antigen processing and presentation: evidence for antigen persistence in non-acidic recycling endosomal compartments","year":2001,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council Canada; Medical Research Council; University of Bristol","keywords":"Endosome; Biology; Internalization; Antigen; Antigen presentation; Endocytic cycle; Antigen processing; Cholera toxin; Vacuole; Lysosome; Cell biology; Phagolysosome; Microbiology; Endocytosis; Phagocytosis; Receptor; Intracellular; Immune system; T cell; Phagosome; Biochemistry; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003515742,0.0002660401,0.0003303828,0.00009545318,0.0002194216,0.00006055518,0.0002038862,0.0002066484,0.000008210403],"category_scores_gemma":[0.0002360963,0.0002695005,0.00005246431,0.0002144351,0.000477624,0.00002623558,0.0003121386,0.0001810297,0.000003534643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003190604,"about_ca_system_score_gemma":0.00007514226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003736892,"about_ca_topic_score_gemma":0.00005306103,"domain_scores_codex":[0.9981863,0.0001653098,0.0003499739,0.0006816407,0.00006804731,0.0005487441],"domain_scores_gemma":[0.999324,0.00008394395,0.0001393511,0.000202798,0.0001334519,0.0001164261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002876951,0.00006485615,0.1161954,0.00009973283,0.00004581663,0.00002285422,0.0004173636,0.000006084171,0.88217,8.876621e-7,0.00004033332,0.0006489892],"study_design_scores_gemma":[0.002408891,0.0005734563,0.04046689,0.0002299975,0.00002119627,0.0000573317,0.0005210708,0.001093881,0.9419466,0.000005687462,0.01226368,0.0004112938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793097,0.01839104,0.0007444156,0.0002559781,0.00006841969,0.0011395,0.0000283671,0.00001358456,0.00004895894],"genre_scores_gemma":[0.9937006,0.003821581,0.001551574,0.0002419985,0.00009761665,0.0001751229,0.0002118036,0.00002821595,0.0001715093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07572849,"threshold_uncertainty_score":0.9999757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04496091512955572,"score_gpt":0.3058966240476834,"score_spread":0.2609357089181277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}