{"id":"W2142478420","doi":"10.1093/hmg/ddl207","title":"Molecular components of the mammalian circadian clock","year":2006,"lang":"en","type":"review","venue":"Human Molecular Genetics","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":1655,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Biology; Suprachiasmatic nucleus; Circadian rhythm; Bacterial circadian rhythms; CLOCK; Circadian clock; Oscillating gene; Cell biology; Clockwork; Light effects on circadian rhythm; Period (music); Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002905969,0.0009209206,0.0007728291,0.001052236,0.0003143546,0.0008110864,0.0009215829,0.0007856544,0.002464635],"category_scores_gemma":[0.0002920467,0.0002703454,0.0002470105,0.001086744,0.0005718237,0.0009428707,0.000552937,0.001180517,0.004006674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007869059,"about_ca_system_score_gemma":0.001104795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001231847,"about_ca_topic_score_gemma":0.0009395781,"domain_scores_codex":[0.9998773,0.00001384867,0.00001641706,0.00002960339,0.00004902565,0.00001379165],"domain_scores_gemma":[0.9999008,0.00001888753,0.00001963476,0.000005508465,0.00003596715,0.00001914845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008185871,0.00003330474,0.0003219664,0.0048791,0.00004138341,0.0003744309,0.00009417828,0.0004501352,0.01622319,0.01228264,0.02498998,0.9402278],"study_design_scores_gemma":[0.000007913502,0.00002957484,0.001048484,0.000514976,0.00002301648,0.0007693836,0.00003329269,0.00005824662,0.002424179,0.002340684,0.992739,0.00001116431],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004148982,0.9927197,0.00108572,0.0003916553,0.0004941653,0.00001539612,0.00006079998,0.00004707327,0.004770758],"genre_scores_gemma":[0.003465602,0.9912344,0.001178451,0.0002031033,0.0003549878,0.00002161971,0.0001178879,0.000005273738,0.003418848],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002464635,"threshold_uncertainty_score":0.008244991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05678196743582137,"score_gpt":0.3043315781705905,"score_spread":0.2475496107347692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}