{"id":"W2142494199","doi":"10.1177/1352458510388543","title":"Intrathecal IgM synthesis in pediatric MS is not a negative prognostic marker of disease progression: quantitative versus qualitative IgM analysis","year":2010,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Multiple sclerosis; Medicine; Intrathecal; Cerebrospinal fluid; Expanded Disability Status Scale; Internal medicine; Gastroenterology; Cohort; Clinically isolated syndrome; Immunology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007371886,0.0003426498,0.0002645421,0.001006664,0.0001610893,0.0003166723,0.0001789426,0.000283898,0.0007216429],"category_scores_gemma":[0.002624226,0.0001248592,0.0002148265,0.0005175378,0.0002889627,0.0003030733,0.0002078563,0.0002859999,0.0001626424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002009475,"about_ca_system_score_gemma":0.0002292395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009149449,"about_ca_topic_score_gemma":0.0008042564,"domain_scores_codex":[0.999686,0.00009640611,0.00003229314,0.00006271213,0.00007555731,0.00004702399],"domain_scores_gemma":[0.9980637,0.0006914067,0.00077627,0.00008312842,0.0001650149,0.0002204478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002661018,0.00001108929,0.9958344,0.00001189642,0.00001691353,0.0001126529,0.00002822808,0.00008819051,0.001233636,0.000008025639,0.00002931625,0.002359582],"study_design_scores_gemma":[0.000008710896,0.0003408043,0.9963164,0.000009757919,0.00003767493,0.00129276,0.0000906921,0.0006578984,0.001013876,0.00002512858,0.0002027749,0.000003423359],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993047,0.000291209,0.0001788146,0.00001008368,0.000002084144,0.000003357255,0.00008419563,0.000004367526,0.0001212549],"genre_scores_gemma":[0.9994966,0.00009031299,0.0002326615,0.000004023045,0.000005301039,0.000005577173,0.0001371988,0.000002171139,0.0000261587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001006664,"threshold_uncertainty_score":0.00389868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1297357486027235,"score_gpt":0.3940297134961396,"score_spread":0.2642939648934161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}