{"id":"W2142496373","doi":"10.1091/mbc.e02-01-0036","title":"Fluorescence Resonance Energy Transfer Detection of Synaptophysin I and Vesicle-associated Membrane Protein 2 Interactions during Exocytosis from Single Live Synapses","year":2002,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca; York University; Harvard University","keywords":"Exocytosis; Biology; Synaptophysin; Förster resonance energy transfer; Vesicle; Munc-18; Synaptotagmin 1; Cell biology; Membrane; Biophysics; Energy transfer; Synaptic vesicle; Vesicle fusion; Fluorescence; Biochemistry; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004625632,0.0001388945,0.0001877908,0.00003552865,0.00006883332,0.000003954352,0.0001426462,0.0001691649,0.00002180331],"category_scores_gemma":[0.00002584902,0.0001217173,0.0001368087,0.00009353598,0.0002091647,0.000004726232,0.00004208808,0.00008530747,7.302379e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001305803,"about_ca_system_score_gemma":0.000007468718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002522695,"about_ca_topic_score_gemma":0.0001311717,"domain_scores_codex":[0.9991229,0.0001369465,0.0002391542,0.0002825172,0.00006896573,0.0001494936],"domain_scores_gemma":[0.9995362,0.00001217338,0.000104064,0.0002595534,0.00005771708,0.00003031952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008990312,0.000144364,0.0003315177,0.00002262245,0.00005597503,0.0000016299,0.00008442193,0.00001814465,0.998722,0.00001044863,6.935937e-7,0.0005182557],"study_design_scores_gemma":[0.0004449838,0.0002030945,0.001759144,0.00005166947,0.00004722621,0.000002672001,0.00002064992,0.0001658231,0.9969369,0.00007013403,0.0001768699,0.0001208937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919428,0.002327617,0.005380713,0.00005083632,0.00006497486,0.0001340128,0.00003489915,0.000007900673,0.00005627436],"genre_scores_gemma":[0.9993558,0.0002362605,0.00009024652,0.00002029518,0.00002079824,0.00001424497,0.0001181739,0.00001577084,0.0001283926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007413046,"threshold_uncertainty_score":0.4963487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006356310211388537,"score_gpt":0.1782838969459969,"score_spread":0.1719275867346084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}