{"id":"W2142581632","doi":"10.1002/chin.200912189","title":"ChemInform Abstract: Sintokamide A to E, Chlorinated Peptides from the Sponge Dysidea sp. that Inhibit Transactivation of the N‐Terminus of the Androgen Receptor in Prostate Cancer Cells.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Chemistry; Transactivation; Androgen receptor; Prostate cancer; Sponge; Cancer; Cancer research; Biochemistry; Internal medicine; Gene; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007008424,0.0006514703,0.0001615184,0.0002970562,0.000170449,0.0002001258,0.0001746322,0.0001650256,0.009676218],"category_scores_gemma":[0.00007143856,0.0001302515,0.0001768878,0.0002433941,0.0001750181,0.0002238445,0.0001335054,0.0003610954,0.002261403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003136897,"about_ca_system_score_gemma":0.0003963824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009118493,"about_ca_topic_score_gemma":0.001475197,"domain_scores_codex":[0.9999604,0.000005331725,0.000002983357,0.000007079749,0.00001630767,0.00000789751],"domain_scores_gemma":[0.9999696,0.000004704735,0.000006791029,0.000002719383,0.000004133784,0.00001203977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000555819,0.00003903762,0.0001265509,0.0003658858,0.00001983834,0.0001845677,0.00001689569,0.0002124011,0.9844431,0.0006211093,0.002312812,0.01110199],"study_design_scores_gemma":[0.0001955879,0.0006059657,0.002817865,0.00002124822,0.00003451308,0.0004728817,0.00002400516,0.0002769978,0.9490461,0.0001832646,0.04630546,0.00001602147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8373495,0.02854053,0.01234675,0.001231444,0.001248613,0.0004948059,0.01267053,0.0009924496,0.1051253],"genre_scores_gemma":[0.8974097,0.01340097,0.006278018,0.0003337214,0.0001352252,0.0001165571,0.009752228,0.0001066998,0.07246694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009676218,"threshold_uncertainty_score":0.03237015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307308362322659,"score_gpt":0.2242689982241762,"score_spread":0.2111959146009496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}