{"id":"W2142581632","doi":"10.1002/chin.200912189","title":"ChemInform Abstract: Sintokamide A to E, Chlorinated Peptides from the Sponge Dysidea sp. that Inhibit Transactivation of the N‐Terminus of the Androgen Receptor in Prostate Cancer Cells.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Chemistry; Transactivation; Androgen receptor; Prostate cancer; Sponge; Cancer; Cancer research; Biochemistry; Internal medicine; Gene; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001990884,0.0001810067,0.0002103575,0.00001455208,0.00005484813,0.00001428161,0.0004194311,0.0001477348,0.00008076692],"category_scores_gemma":[0.000102328,0.00008613721,0.0001617465,0.0001955804,0.0001241884,0.00001557814,0.00007961009,0.0001366349,0.000001340538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004610432,"about_ca_system_score_gemma":0.0000735365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003700203,"about_ca_topic_score_gemma":0.0001962071,"domain_scores_codex":[0.9990712,0.000001142774,0.0003224633,0.0002058085,0.000185685,0.0002136488],"domain_scores_gemma":[0.9991822,0.00005213655,0.0002619488,0.0003940416,0.00006973439,0.00003992357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000222408,0.00006381776,0.002214213,0.0000150203,0.00001960846,2.293591e-7,0.0003766973,0.000002956703,0.8280912,0.000002042722,0.0005682288,0.1684236],"study_design_scores_gemma":[0.0002405338,0.00005276119,0.133998,0.00008990273,0.00001196267,0.00000113817,0.0001602927,0.000001489042,0.8598323,0.0000319205,0.005467754,0.0001119713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990111,0.0001127165,1.47339e-7,0.0007218092,0.00006471363,0.0004566961,0.0001476986,0.000005002024,0.008380239],"genre_scores_gemma":[0.9986322,0.0001175608,0.000009557718,0.0003353846,0.00005800157,0.00003451909,0.00002573585,0.00000739087,0.0007796355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1683116,"threshold_uncertainty_score":0.3512574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307308362322659,"score_gpt":0.2242689982241762,"score_spread":0.2111959146009496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}