{"id":"W2142605524","doi":"10.1091/mbc.e04-03-0178","title":"A Human Telomerase-associated Nuclease","year":2004,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Amgen","keywords":"Biology; Telomerase; Nuclease; Primer (cosmetics); Processivity; DNA; Telomerase RNA component; Biochemistry; Telomere; Oligonucleotide; Primer extension; DNA polymerase; Molecular biology; Cell biology; Telomerase reverse transcriptase; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003300335,0.0002658087,0.0002773334,0.000243196,0.000216114,0.0004556403,0.0001815217,0.0004593234,0.001860522],"category_scores_gemma":[0.0004518978,0.0001158886,0.0003253787,0.0001863275,0.0002059793,0.000179052,0.0002486444,0.0003935861,0.0007910376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000316366,"about_ca_system_score_gemma":0.0004966931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003318938,"about_ca_topic_score_gemma":0.0004924437,"domain_scores_codex":[0.9997743,0.0000340925,0.00001817809,0.0000800784,0.00006648445,0.00002683311],"domain_scores_gemma":[0.999854,0.00003923078,0.00002141007,0.00002862136,0.0000195412,0.00003714729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001114136,0.00003534725,0.0006224633,0.00009587812,0.00001837178,0.0001174069,0.00002377513,0.0001199323,0.9805172,0.0007777394,0.0002952347,0.01726523],"study_design_scores_gemma":[0.00003325102,0.0003888117,0.005011065,0.0000233284,0.00003598188,0.00222764,0.0000150374,0.0009389903,0.9529691,0.0004381289,0.037905,0.00001356766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8800793,0.02792817,0.07431246,0.0004648899,0.0004636681,0.0003694122,0.002874451,0.0009951327,0.01251243],"genre_scores_gemma":[0.9240078,0.004309885,0.04635093,0.0002238237,0.00005649541,0.0001388955,0.007602647,0.00004288666,0.01726664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001860522,"threshold_uncertainty_score":0.006224096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008892734361389102,"score_gpt":0.2594895240798487,"score_spread":0.2505967897184596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}