{"id":"W2142684817","doi":"10.1038/nature02099","title":"An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"Hepatitis C virus research","field":"Medicine","cited_by":913,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"NS3; Hepatitis C virus; Virology; Protease inhibitor (pharmacology); Protease; Hepatitis C; Medicine; Ribavirin; Virus; Hepacivirus; Interferon; Immunology; Pharmacology; Biology; Viral load; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003085283,0.000158632,0.0003654936,0.0001453152,0.000334697,0.0002220947,0.00009997311,0.0003614205,0.0008472331],"category_scores_gemma":[0.0004022401,0.0001269494,0.000165221,0.0001235325,0.000247723,0.000149298,0.00006862694,0.0004371319,0.0001237608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002291896,"about_ca_system_score_gemma":0.0002280583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001060451,"about_ca_topic_score_gemma":0.001191704,"domain_scores_codex":[0.9999166,0.00003909247,0.000004719405,0.000007017422,0.00001744039,0.00001513145],"domain_scores_gemma":[0.999872,0.00004553155,0.00002193697,0.00001057131,0.00001329578,0.00003657572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.08042931,0.003371054,0.08310792,0.0007409581,0.0004215986,0.004890393,0.0005817261,0.0006628661,0.5504142,0.000913047,0.003909547,0.2705574],"study_design_scores_gemma":[0.006511802,0.1157875,0.4907455,0.0001285535,0.001419811,0.02181861,0.0007631687,0.003079899,0.2985472,0.001376658,0.05974431,0.00007704138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810017,0.01369848,0.0004395252,0.000358385,0.00007564689,0.0000536901,0.0001080222,0.00002665483,0.004237995],"genre_scores_gemma":[0.9955809,0.00254429,0.0004208077,0.0001849365,0.00006822385,0.00001636495,0.00008799418,0.000005131184,0.001091363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001060451,"threshold_uncertainty_score":0.00283426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006832773382691644,"score_gpt":0.292989150956293,"score_spread":0.2861563775736014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}