{"id":"W2142704920","doi":"10.1128/jvi.77.20.11170-11179.2003","title":"T-Cell Receptor/CD28 Engagement When Combined with Prostaglandin E<sub>2</sub>Treatment Leads to Potent Activation of Human T-Cell Leukemia Virus Type 1","year":2003,"lang":"en","type":"article","venue":"Journal of Virology","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Biology; CD28; Jurkat cells; Reporter gene; Long terminal repeat; Molecular biology; T-cell receptor; T cell; Transfection; Gene expression; Cell biology; Gene; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004069272,0.0002793479,0.0006453327,0.0002554891,0.0002303371,0.000008159249,0.0001721079,0.0002470024,0.0001555945],"category_scores_gemma":[0.0000444162,0.0001874048,0.0001284423,0.0001408009,0.0001788932,0.00006639904,0.00005300761,0.0004173505,0.0001136593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003240238,"about_ca_system_score_gemma":0.0001955135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004298199,"about_ca_topic_score_gemma":0.00004238719,"domain_scores_codex":[0.998221,0.0004571707,0.0006054315,0.000241117,0.00008967446,0.0003855551],"domain_scores_gemma":[0.9987234,0.000115863,0.0006481832,0.0002224964,0.0002332847,0.00005676946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00236386,0.0008422471,0.006152433,0.00002716658,0.0003514558,0.00001395626,0.001272325,0.0001429706,0.9820041,0.0001324895,0.006301025,0.0003959626],"study_design_scores_gemma":[0.005111993,0.01820463,0.001924891,0.00002944445,0.0001595142,0.00004328757,0.000310863,3.312063e-7,0.9582842,0.00006836559,0.01567644,0.000186071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963983,0.0009573131,0.0001265142,0.0002439103,0.0006103519,0.000367751,0.000009143795,0.00001428648,0.001272431],"genre_scores_gemma":[0.9977529,0.0004119215,0.0002887099,0.0001947776,0.0000468918,0.00001250131,0.00001808905,0.00002566966,0.001248539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02371993,"threshold_uncertainty_score":0.7642148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01615019458458408,"score_gpt":0.2295669234586455,"score_spread":0.2134167288740615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}