{"id":"W2142743355","doi":"10.1002/chin.200342136","title":"Enantioselective Synthesis of 3‐Substituted‐4‐aryl Piperidines Useful for the Preparation of Paroxetine.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brantford Energy (Canada)","funders":"","keywords":"Chemistry; Enantioselective synthesis; Aryl; Paroxetine; Combinatorial chemistry; Stereochemistry; Organic chemistry; Catalysis; Serotonin; Alkyl; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002555347,0.0001413168,0.0002889839,0.00005303878,0.00007534777,0.00001019168,0.000210916,0.000100941,0.0001881804],"category_scores_gemma":[0.00209343,0.00009701143,0.0002237534,0.0003239646,0.00009800132,0.000104045,0.00001840498,0.00004730128,0.000003144637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000359749,"about_ca_system_score_gemma":0.00007822386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000018396,"about_ca_topic_score_gemma":0.000003238978,"domain_scores_codex":[0.9990733,5.424794e-7,0.00040465,0.0001586406,0.0001925677,0.0001703211],"domain_scores_gemma":[0.9980031,0.001027697,0.000346307,0.000378352,0.0002112973,0.0000332546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005804978,0.0005910706,0.006544083,0.001760963,0.001578644,8.130007e-7,0.002369432,0.00004389061,0.2387506,0.005816431,0.01085826,0.7311053],"study_design_scores_gemma":[0.0001685412,0.000009670047,0.0001510627,0.0000380889,0.0002023566,0.000002736559,0.0007001762,0.00009719947,0.9853914,0.00005487004,0.01307172,0.000112184],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.2209844,0.001371038,0.0003185126,0.00006825892,0.0001059341,0.0003658647,0.0001247665,0.00005760971,0.7766036],"genre_scores_gemma":[0.9979938,0.0001288561,0.0001477904,0.00000557415,0.00004911389,0.0001690922,0.00001539544,0.00001330129,0.001477107],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7770094,"threshold_uncertainty_score":0.3956011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01453726203297796,"score_gpt":0.2480750271209547,"score_spread":0.2335377650879768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}