{"id":"W2142750170","doi":"10.1016/j.bbmt.2010.01.009","title":"Tumor Necrosis Factor-α Gene Polymorphisms Are Associated with Severity of Acute Graft-Versus-Host Disease Following Matched Unrelated Donor Bone Marrow Transplantation in Children: A Pediatric Blood and Marrow Transplant Consortium Study","year":2010,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Graft-versus-host disease; Allele; Internal medicine; Hazard ratio; Transplantation; Methotrexate; Single-nucleotide polymorphism; Immunology; Gastroenterology; Tacrolimus; Genotype; Bone marrow; Tumor necrosis factor alpha; Gene; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006266384,0.0005927145,0.0006647998,0.0007817586,0.0005663721,0.0006675714,0.0004953773,0.0004684125,0.000806155],"category_scores_gemma":[0.002157663,0.0004118842,0.0006510684,0.001264262,0.0006738726,0.0004319515,0.0004733645,0.0008997854,0.000157427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004741982,"about_ca_system_score_gemma":0.0005577328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00400535,"about_ca_topic_score_gemma":0.002993428,"domain_scores_codex":[0.9992348,0.0002478132,0.0000970519,0.0001426938,0.0001477727,0.0001297439],"domain_scores_gemma":[0.998094,0.0003852895,0.0008837955,0.0001302235,0.0001303392,0.0003764077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003014694,0.00008668344,0.9966887,0.00000835314,0.00009029965,0.0004696301,0.0001610748,0.00006537465,0.001484985,0.00002985279,0.00004787895,0.0005656742],"study_design_scores_gemma":[0.00002582133,0.0002982075,0.996194,0.000005405909,0.00009190996,0.002187721,0.0003562655,0.000155874,0.0005312476,0.00002685962,0.0001204128,0.000006246289],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997881,0.00003476533,0.00003616191,0.00001349002,0.000002128595,0.000002452951,0.00006450986,0.000001064569,0.00005738304],"genre_scores_gemma":[0.9996779,0.00005698986,0.00006943676,0.00001087688,0.000006217066,0.000004999023,0.0001129834,0.000002228073,0.00005841343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00400535,"threshold_uncertainty_score":0.007964075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008433862018201697,"score_gpt":0.2290946654856945,"score_spread":0.2206608034674928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}