{"id":"W2142814377","doi":"10.1182/blood-2011-04-345256","title":"Prognostic significance of immunohistochemical biomarkers in diffuse large B-cell lymphoma: a study from the Lunenburg Lymphoma Biomarker Consortium","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Genentech; National Institute for Health and Care Research; Eli Lilly and Company","keywords":"Rituximab; International Prognostic Index; Medicine; BCL6; Diffuse large B-cell lymphoma; Internal medicine; Oncology; Lymphoma; Biomarker; Pathology; Immunology; B cell; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002038737,0.0002818322,0.0003949894,0.001310812,0.0003333824,0.0008679309,0.0002467849,0.0003322705,0.0005005176],"category_scores_gemma":[0.004295725,0.000200346,0.0002573843,0.001212541,0.0002624319,0.0003175597,0.0004795915,0.0002679783,0.0001493772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005208387,"about_ca_system_score_gemma":0.0003249212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001567237,"about_ca_topic_score_gemma":0.001886493,"domain_scores_codex":[0.9992462,0.0004058507,0.00005450867,0.0001262544,0.0001058661,0.00006126097],"domain_scores_gemma":[0.9985448,0.0005188562,0.000384385,0.0001234999,0.0002041998,0.0002243067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001433913,0.00006962435,0.9859153,0.00002282432,0.0002353091,0.000124702,0.00007058513,0.0001345283,0.000978986,0.00004726558,0.0003393221,0.01062765],"study_design_scores_gemma":[0.0004982462,0.0006347645,0.9920833,0.00003242241,0.0004327261,0.001256736,0.0001809332,0.00111919,0.001138797,0.0001385159,0.002467073,0.00001732962],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980763,0.001174291,0.0001763302,0.0001032306,0.000005201259,0.00001424011,0.0002059473,0.000002597361,0.0002417429],"genre_scores_gemma":[0.9986317,0.0002615034,0.0003023989,0.00006629367,0.00002588306,0.0000187604,0.0005862089,0.00000229508,0.0001051441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038737,"threshold_uncertainty_score":0.010782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02218879087789223,"score_gpt":0.2473049939326845,"score_spread":0.2251162030547923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}