{"id":"W2142855333","doi":"10.1128/iai.73.4.2061-2074.2005","title":"Redundant Roles for Met Docking Site Tyrosines and the Gab1 Pleckstrin Homology Domain in InlB-Mediated Entry of <i>Listeria monocytogenes</i>","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Liver physiology and pathology","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Pleckstrin homology domain; Biology; Listeria monocytogenes; Homology modeling; Docking (animal); Computational biology; Cell biology; Sequence homology; Plasma protein binding; Microbiology; Peptide sequence; Biochemistry; Genetics; Signal transduction; Bacteria; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001359019,0.000357399,0.0002535378,0.0001542822,0.0001512962,0.0004628413,0.0002664692,0.000332467,0.0004805519],"category_scores_gemma":[0.0001230138,0.0002507879,0.0002342144,0.0001037039,0.0002379507,0.0002194912,0.0003986647,0.0003414045,0.000365574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003989452,"about_ca_system_score_gemma":0.0002576898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008232355,"about_ca_topic_score_gemma":0.0008197387,"domain_scores_codex":[0.9998722,0.00002493625,0.00001616066,0.00001669592,0.0000271836,0.0000427685],"domain_scores_gemma":[0.9998641,0.00001562161,0.00004987882,0.00001418,0.0000116355,0.00004456911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001985875,0.00001475517,0.0003343386,0.00001889668,0.000002775221,0.00008386626,0.00001418911,0.00005015043,0.9988027,0.0001574451,0.000009397115,0.0003129119],"study_design_scores_gemma":[0.00006848283,0.0002184077,0.0199826,0.0000129055,0.00003169649,0.001047421,0.00009961789,0.002816953,0.9741259,0.0001104145,0.001474201,0.00001144324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989057,0.0002854652,0.000392042,0.00003314858,0.000004079907,0.000003842545,0.0000516136,0.00001144049,0.0003126575],"genre_scores_gemma":[0.9985548,0.0001606925,0.0005730275,0.00002847123,0.000002640485,0.000006543259,0.0001935717,0.000008198018,0.0004721185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008232355,"threshold_uncertainty_score":0.00289458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684634036457405,"score_gpt":0.2774208207731337,"score_spread":0.2605744804085596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}