{"id":"W2142865224","doi":"10.1165/rcmb.2010-0450oc","title":"Steroid-Insensitive ERK1/2 Activity Drives CXCL8 Synthesis and Neutrophilia by Airway Smooth Muscle","year":2011,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Christie (Canada)","funders":"","keywords":"Neutrophilia; Interleukin 8; Airway; Medicine; Internal medicine; Cardiology; Chemistry; Inflammation; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141998,0.0002396695,0.0001675541,0.00009578787,0.0001170612,0.0002096253,0.0001221818,0.0001588848,0.001861507],"category_scores_gemma":[0.00007693805,0.0001355951,0.0002661871,0.0000801638,0.0001656264,0.0001421513,0.0001791163,0.0005139781,0.0003720231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145252,"about_ca_system_score_gemma":0.0001716247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003217529,"about_ca_topic_score_gemma":0.0006253532,"domain_scores_codex":[0.9998565,0.0000247786,0.00001085029,0.00002763495,0.00003067555,0.00004958813],"domain_scores_gemma":[0.9999449,0.000007693293,0.00001603711,0.000008042566,0.000005813586,0.00001736517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008999019,0.00002813261,0.0001209065,0.00003751024,0.00000235456,0.00002771596,0.000007291677,0.00001957288,0.9990415,0.00004272054,0.00003489943,0.0005474133],"study_design_scores_gemma":[0.00005548209,0.0006167015,0.02202918,0.00001410178,0.00001301977,0.0005365799,0.00008728667,0.001812103,0.9709761,0.0001304421,0.003722044,0.000007106111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957076,0.001429852,0.001145522,0.0001454462,0.00004327093,0.00002457777,0.0003326487,0.00003350179,0.001137457],"genre_scores_gemma":[0.9953667,0.0007577944,0.0008938964,0.00007839374,0.00001781834,0.00003564607,0.0005107182,0.000007716809,0.00233125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861507,"threshold_uncertainty_score":0.006227374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0071639300547167,"score_gpt":0.213496968354143,"score_spread":0.2063330382994263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}