{"id":"W2142896923","doi":"10.1083/jcb.201210019","title":"Global analysis of SUMO chain function reveals multiple roles in chromatin regulation","year":2013,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Chromatin; Mutant; Ubiquitin; Saccharomyces cerevisiae; SUMO protein; Gene; Genetics; Cell biology; Psychological repression; ChIA-PET; Function (biology); Yeast; Gene expression; Computational biology; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001533552,0.0003148471,0.0002862921,0.0004182732,0.0001700208,0.0003995607,0.0001309665,0.0001491762,0.000803402],"category_scores_gemma":[0.0001192846,0.0001281086,0.000283645,0.000306251,0.0002419046,0.0002509642,0.0002204857,0.0002646112,0.0001688985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002042187,"about_ca_system_score_gemma":0.0001089528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003999551,"about_ca_topic_score_gemma":0.001110581,"domain_scores_codex":[0.999925,0.000007174297,0.000006089037,0.0000280432,0.00002171222,0.00001193655],"domain_scores_gemma":[0.9998602,0.00003767274,0.0000329961,0.00002283118,0.00001986744,0.00002644287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007517688,0.000003125396,0.002069361,0.00002676974,0.00001093105,0.00001597668,0.00000659492,0.00008739528,0.9961753,0.00006093993,0.000008979712,0.001459382],"study_design_scores_gemma":[0.00000347702,0.00008606268,0.04221813,0.000003664348,0.00004537374,0.0001229264,0.00003389183,0.000865263,0.9558452,0.0001303871,0.0006406123,0.00000494087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923949,0.001274319,0.005077452,0.00003077261,0.000004210453,0.000008087298,0.0007009279,0.00005398192,0.0004553272],"genre_scores_gemma":[0.9948968,0.0007467797,0.002871453,0.00001856231,0.000003918154,0.000008834017,0.000863032,0.00001816665,0.0005723523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000803402,"threshold_uncertainty_score":0.002687693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00852666701378888,"score_gpt":0.2298372619034496,"score_spread":0.2213105948896608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}