{"id":"W2142909984","doi":"10.1093/hmg/ddv378","title":"Integrative pathway genomics of lung function and airflow obstruction","year":2015,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; National Heart, Lung, and Blood Institute; Medical Research Council","keywords":"Genome-wide association study; Biology; Genetic association; Candidate gene; Genetics; Computational biology; Population; Quantitative trait locus; Phenotype; Gene; Single-nucleotide polymorphism; Medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148223,0.0001657123,0.0002385518,0.0001425546,0.00006323252,0.00001595922,0.00007130811,0.00009907073,0.00004567027],"category_scores_gemma":[0.00006337694,0.0001594144,0.00007719991,0.00014822,0.0002296747,0.00003896137,0.00009695633,0.000225942,0.000006806942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002626257,"about_ca_system_score_gemma":0.0002540937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002198586,"about_ca_topic_score_gemma":0.000007840858,"domain_scores_codex":[0.9987771,0.00009425412,0.0002468163,0.000299727,0.0003714678,0.0002106368],"domain_scores_gemma":[0.9989298,0.00001355432,0.00008718557,0.0003426613,0.000361231,0.0002655938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006312416,0.0004532922,0.06897494,0.0006763783,0.00045549,0.0001836133,0.001781816,0.0004115602,0.8883409,0.007657019,0.0005528827,0.02988089],"study_design_scores_gemma":[0.006082641,0.001747361,0.8540816,0.0001972567,0.0005788918,0.0001841241,0.002993998,0.01170386,0.09970237,0.01868701,0.003457471,0.0005833954],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895918,0.003847972,0.003630931,0.00004614674,0.0001193012,0.0004494286,0.00001712375,0.00002607876,0.002271228],"genre_scores_gemma":[0.9978476,0.00005779968,0.001574255,0.00004445044,0.0001002772,0.00001456535,0.00007554155,0.00003720197,0.0002483042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7886385,"threshold_uncertainty_score":0.6500731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0214745406870717,"score_gpt":0.2846676159528336,"score_spread":0.2631930752657619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}