{"id":"W2142931549","doi":"10.1100/2012/205038","title":"Genomic Profiling of a Human Leukemic Monocytic Cell-Line (THP-1) Exposed to Alpha Particle Radiation","year":2012,"lang":"en","type":"article","venue":"The Scientific World JOURNAL","topic":"Radiation Therapy and Dosimetry","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"THP1 cell line; Gene expression profiling; Gene expression; Gene; Immune system; Downregulation and upregulation; Microarray; Biology; Cell culture; Candidate gene; Molecular biology; Cancer research; Computational biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014989,0.0001707399,0.0003034122,0.000393491,0.000208317,0.0002313039,0.00006954955,0.0002068362,0.0007259367],"category_scores_gemma":[0.0001868351,0.0001183555,0.0002207543,0.00043967,0.0001947799,0.00009848801,0.0001231385,0.0002534568,0.0002774019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001517231,"about_ca_system_score_gemma":0.0001507831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005469634,"about_ca_topic_score_gemma":0.0008650697,"domain_scores_codex":[0.9998832,0.00002044953,0.00000586497,0.00003377936,0.00003659201,0.00002013865],"domain_scores_gemma":[0.9998904,0.000028427,0.00003014506,0.00001343455,0.00002431745,0.00001321129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009616279,0.000007344673,0.001589966,0.00002593731,0.000004293202,0.00004164681,0.00003345059,0.00004312367,0.9973579,0.00001005598,0.00001759263,0.0007725141],"study_design_scores_gemma":[0.00001534505,0.001067944,0.3103512,0.00001632442,0.00008842506,0.001002617,0.0004481615,0.0007874704,0.683429,0.0001068273,0.002670411,0.00001631807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937149,0.001087786,0.00259965,0.00007123396,0.0000154088,0.00003313761,0.001904474,0.00002900655,0.0005445001],"genre_scores_gemma":[0.9880587,0.001659469,0.004899064,0.0001165322,0.0000200845,0.00007724152,0.003457931,0.00001245121,0.001698411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007259367,"threshold_uncertainty_score":0.002428472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04206137689129625,"score_gpt":0.3071717302777401,"score_spread":0.2651103533864438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}