{"id":"W2142931549","doi":"10.1100/2012/205038","title":"Genomic Profiling of a Human Leukemic Monocytic Cell-Line (THP-1) Exposed to Alpha Particle Radiation","year":2012,"lang":"en","type":"article","venue":"The Scientific World JOURNAL","topic":"Radiation Therapy and Dosimetry","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"THP1 cell line; Gene expression profiling; Gene expression; Gene; Immune system; Downregulation and upregulation; Microarray; Biology; Cell culture; Candidate gene; Molecular biology; Cancer research; Computational biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002349286,0.0001086042,0.000195478,0.0003017125,0.0004855286,0.00009544593,0.0001931132,0.00002710059,0.0003235468],"category_scores_gemma":[0.00005512803,0.00007525658,0.0001158277,0.0007817204,0.0001038183,0.0001981402,0.00002841307,0.0002468893,0.0001379653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002118323,"about_ca_system_score_gemma":0.0001412972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004688644,"about_ca_topic_score_gemma":0.0000027059,"domain_scores_codex":[0.9985004,0.0001184508,0.000477417,0.0001455637,0.0003856628,0.0003725252],"domain_scores_gemma":[0.9989617,0.00006522513,0.0002544564,0.0003434018,0.00009872842,0.000276424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001148598,0.0001428927,0.0151025,0.00001524895,0.00002985461,0.000001432825,0.00227834,0.0004970981,0.9758818,0.0001843789,0.00147463,0.00427695],"study_design_scores_gemma":[0.001336571,0.0001801248,0.02705626,0.00004207325,0.00009855918,0.0000541689,0.0003350112,0.002083852,0.967012,0.0002292428,0.001460689,0.0001114541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954988,0.001646725,0.0004240829,0.0007425873,0.0009277042,0.0003370717,0.000002586698,0.00002187605,0.0003985835],"genre_scores_gemma":[0.9923291,0.0000135682,0.000549473,0.0002902453,0.0006475628,0.000006004533,0.000006072666,0.00001709219,0.006140835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01195376,"threshold_uncertainty_score":0.3734343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04206137689129625,"score_gpt":0.3071717302777401,"score_spread":0.2651103533864438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}